[HTML][HTML] Mortality results from a randomized prostate-cancer screening trial

…, ED Crawford, RL Grubb III, SS Buys… - New England journal …, 2009 - Mass Medical Soc
Background The effect of screening with prostate-specific–antigen (PSA) testing and digital
rectal examination on the rate of death from prostate cancer is unknown. This is the first …

Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers

…, WK Chung, IL Andrulis, M Southey, MB Daly, SS Buys… - Jama, 2017 - jamanetwork.com
Importance The clinical management ofBRCA1andBRCA2mutation carriers requires accurate,
prospective cancer risk estimates. Objectives To estimate age-specific risks of breast, …

A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer

…, GA Colditz, RG Ziegler, CD Berg, SS Buys… - Nature …, 2007 - nature.com
We conducted a genome-wide association study (GWAS) of breast cancer by genotyping
528,173 SNPs in 1,145 postmenopausal women of European ancestry with invasive breast …

Effect of screening on ovarian cancer mortality: the prostate, lung, colorectal and ovarian (PLCO) cancer screening randomized controlled trial

SS Buys, E Partridge, A Black, CC Johnson… - Jama, 2011 - jamanetwork.com
Context Screening for ovarian cancer with cancer antigen 125 (CA-125) and transvaginal
ultrasound has an unknown effect on mortality. Objective To evaluate the effect of screening for …

Prostate cancer screening in the randomized Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of follow-up

…, ED Crawford, RL Grubb III, SS Buys… - Journal of the …, 2012 - academic.oup.com
Background The prostate component of the Prostate, Lung, Colorectal, and Ovarian (PLCO)
Cancer Screening Trial was undertaken to determine whether there is a reduction in …

Risk of pancreatic cancer in breast cancer families from the breast cancer family registry

…, IL Andrulis, WK Chung, M Daly, SS Buys… - … , biomarkers & prevention, 2013 - AACR
Background: Increased risk of pancreatic cancer has been reported in breast cancer
families carrying BRCA1and BRCA2 mutations; however, pancreatic cancer risk in mutation-…

Genetic/familial high-risk assessment: breast, ovarian, and pancreatic, version 2.2021, NCCN clinical practice guidelines in oncology

MB Daly, T Pal, MP Berry, SS Buys, P Dickson… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Genetic/Familial High-Risk Assessment: Breast, Ovarian, and
Pancreatic focus primarily on assessment of pathogenic or likely pathogenic variants associated …

[HTML][HTML] Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy

…, R Bresalier, GL Andriole, SS Buys… - … England Journal of …, 2012 - Mass Medical Soc
Background The benefits of endoscopic testing for colorectal-cancer screening are uncertain.
We evaluated the effect of screening with flexible sigmoidoscopy on colorectal-cancer …

Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes

YS DeRose, G Wang, YC Lin, PS Bernard, SS Buys… - Nature medicine, 2011 - nature.com
Abstract Development and preclinical testing of new cancer therapies is limited by the scarcity
of in vivo models that authentically reproduce tumor growth and metastatic progression. …

[HTML][HTML] Breast-Cancer Risk in Families with Mutations in PALB2

…, A Kallioniemi, GJ Lindeman, SS Buys… - … England Journal of …, 2014 - Mass Medical Soc
Background Germline loss-of-function mutations in PALB2 are known to confer a predisposition
to breast cancer. However, the lifetime risk of breast cancer that is conferred by such …