The speed of muscle contraction is related to body size; muscles in larger species contract
at slower rates. Since contraction speed is a property of the myosin isoform expressed in a …

Nontargeted LC-MS metabolomics datasets contain a wealth of information but present
many challenges during analysis and processing. Often, more than two independently …

The speed of muscle contraction is related to body size; muscles in larger species contract
at a slower rate. We investigated the evolution of twelve myosin II isoforms across mammals …

The speed of muscle contraction is related to body size; muscles in larger species contract
at a slower rate. We investigated the evolution of twelve myosin II isoforms across mammals …

Objective To analyse explanted endografts (EGs) and describe fabric degradation
responsible for type IIIb endoleaks. Methods As part of the European collaborative retrieval …

… Critically, all ferroptosis inhibitors could fully rescue the loss of LT- and ST-HSCs due to …
The resultant loss of LTand ST-HSCs can be rescued by inhibiting ferroptosis with ferrostatin-1 (…

LFA-1 (CD18, CD11a) is a cell-adhesion molecule that mediates critical immunological
processes. In this paper we report the discovery and characterization of (R)-5-(4-bromobenzyl)-3-…

Objective To identify prediagnostic plasma metabolomic biomarkers associated with
amyotrophic lateral sclerosis (ALS). Methods We conducted a global metabolomic study using a …

In epidemiological studies, samples are often collected long before disease onset or
outcome assessment. Understanding the long-term stability of biomarkers measured in these …

Known modifiable risk factors account for a small fraction of premenopausal breast cancers.
We investigated associations between pre-diagnostic circulating amino acid and amino acid-…