Naïve and primed pluripotent states retain distinct molecular properties, yet limited knowledge
exists on how their state transitions are regulated. Here, we identify Mettl3, an N 6 -…

Mouse embryonic stem (ES) cells are isolated from the inner cell mass of blastocysts, and can
be preserved in vitro in a naive inner-cell-mass-like configuration by providing exogenous …

… To further support reduction in rate-limiting barrier(s) on Mbd3 depletion, we modelled
the dynamics of the OSKM reprogramming process using a multi-step Markov chain model (phase-…

… Similar associations of more m 6 As in mRNAs with shorter T 1/2 s were obtained using the
earlier T 1/2 data of our group from human hepatoma cell (Supplemental Fig. 10B; Yang et al. …

… Cells were then fragmented with a Branson Sonifier (model S-450D) at −4 C to a size range
between 200–800 bp, and precipitated by centrifugation. Ten micrograms of each antibody …

… The P values were calculated using a two-sided Student’s t-test. d, Immunoblot analysis of
HCMV immediate-early (IE1-pp72) protein (upper panel) and fluorescence microscopy of GFP …

… In this study, we aimed to elucidate the role of m6A/m in the context of the brain’s stress
response. We delineated the effects of acute stress on m6A/m using global m6A/m …

… FPM calls (two in Geula's data set), and at least one FPM call >3 (0.5 in Geula's data set), …
GWY's interest(s) have been reviewed and approved by the University of California at San …

… Benvenisty and S. Bar for RNA-seq-based karyotyping and SNP analysis, R. Jaenisch for …
Kit according to manufacturer’s instructions but in HENSM conditions applied starting from day …

… Stimulated and unstimulated control cells were harvested into TRIzol (Invitrogen) and
RNA was isolated according to the manufacturer’s instructions. The samples were reverse …