Global analysis of protein expression in yeast
S Ghaemmaghami, WK Huh, K Bower, RW Howson… - Nature, 2003 - nature.com
The availability of complete genomic sequences and technologies that allow comprehensive
analysis of global expression profiles of messenger RNA 1 , 2 , 3 have greatly expanded …
analysis of global expression profiles of messenger RNA 1 , 2 , 3 have greatly expanded …
[HTML][HTML] A first case of acute cerebellitis associated with coronavirus disease (COVID-19): a case report and literature review
N Fadakar, S Ghaemmaghami, SM Masoompour… - The Cerebellum, 2020 - Springer
Novel coronavirus (severe acute respiratory syndrome-coronavirus-2: SARS-CoV-2), which
originated from Wuhan, China, has spread to the other countries in a short period of time. We …
originated from Wuhan, China, has spread to the other countries in a short period of time. We …
Genome-wide analysis in vivo of translation with nucleotide resolution using ribosome profiling
NT Ingolia, S Ghaemmaghami, JRS Newman… - science, 2009 - science.org
Techniques for systematically monitoring protein translation have lagged far behind
methods for measuring messenger RNA (mRNA) levels. Here, we present a ribosome-profiling …
methods for measuring messenger RNA (mRNA) levels. Here, we present a ribosome-profiling …
Analysis of proteome dynamics in the mouse brain
…, SB Prusiner, S Ghaemmaghami - Proceedings of the …, 2010 - National Acad Sciences
… Considerable effort is expended to protect today’s children from lead exposure, but there
is little evidence on the harms past lead exposures continue to hold for yesterday’s children, …
is little evidence on the harms past lead exposures continue to hold for yesterday’s children, …
Single-cell proteomic analysis of S. cerevisiae reveals the architecture of biological noise
JRS Newman, S Ghaemmaghami, J Ihmels… - Nature, 2006 - nature.com
A major goal of biology is to provide a quantitative description of cellular behaviour. This task,
however, has been hampered by the difficulty in measuring protein abundances and their …
however, has been hampered by the difficulty in measuring protein abundances and their …
Incomplete excision of cervical precancer as a predictor of treatment failure: a systematic review and meta-analysis
…, S Ghaem-Maghami, KU Petry, S Leeson… - The Lancet …, 2017 - thelancet.com
Background Incomplete excision of cervical precancer is associated with therapeutic failure
and is therefore considered as a quality indicator of clinical practice. Conversely, the risk of …
and is therefore considered as a quality indicator of clinical practice. Conversely, the risk of …
A quantitative, high-throughput screen for protein stability
S Ghaemmaghami, MC Fitzgerald… - Proceedings of the …, 2000 - National Acad Sciences
In proteomic research, it is often necessary to screen a large number of polypeptides for the
presence of stable structure. Described here is a technique (referred to as SUPREX, stability …
presence of stable structure. Described here is a technique (referred to as SUPREX, stability …
Quantitative protein stability measurement in vivo
S Ghaemmaghami, TG Oas - Nature structural biology, 2001 - nature.com
The equilibrium between the native and denatured states of a protein can be key to its function
and regulation. Traditionally, the folding equilibrium constant has been measured in vitro …
and regulation. Traditionally, the folding equilibrium constant has been measured in vitro …
[HTML][HTML] Continuous quinacrine treatment results in the formation of drug-resistant prions
S Ghaemmaghami, M Ahn, P Lessard, K Giles… - PLoS …, 2009 - journals.plos.org
… Treated mice will be referred to as S[ab] or S[a>], for which “S” is the mouse strain, “a”
indicates the initiation of quinacrine in dpi, “b” indicates the cessation of treatment in dpi, and “>” …
indicates the initiation of quinacrine in dpi, “b” indicates the cessation of treatment in dpi, and “>” …
Discovery of 2-aminothiazoles as potent antiprion compounds
S Ghaemmaghami, BCH May, AR Renslo… - Journal of …, 2010 - Am Soc Microbiol
… Dose-response curves and EC 50 s were computed using SigmaPlot (SPSS, Chicago, IL). …
de Groote, S. Visser, and AP IJzerman. 2001. … Sina Ghaemmaghami …
de Groote, S. Visser, and AP IJzerman. 2001. … Sina Ghaemmaghami …