Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

…, S Jalloh, M Momoh, M Fullah, G Dudas, S Wohl… - science, 2014 - science.org
In its largest outbreak, Ebola virus disease is spreading through Guinea, Liberia, Sierra Leone,
and Nigeria. We sequenced 99 Ebola virus genomes from 78 patients in Sierra Leone to …

[HTML][HTML] Clinical illness and outcomes in patients with Ebola in Sierra Leone

…, DS Grant, C Happi, SM Gevao… - New England journal …, 2014 - Mass Medical Soc
Background Limited clinical and laboratory data are available on patients with Ebola virus
disease (EVD). The Kenema Government Hospital in Sierra Leone, which had an existing …

Virus genomes reveal factors that spread and sustained the Ebola epidemic

…, LS Fakoli, O Faye, ML Gilbert, SM Gevao, S Gire… - Nature, 2017 - nature.com
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented
magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of …

[HTML][HTML] Ebola virus epidemiology, transmission, and evolution during seven months in Sierra Leone

…, GF Palacios, D Ndiaye, C Happi, SM Gevao… - Cell, 2015 - cell.com
The 2013–2015 Ebola virus disease (EVD) epidemic is caused by the Makona variant of
Ebola virus (EBOV). Early in the epidemic, genome sequencing provided insights into virus …

[HTML][HTML] Most neutralizing human monoclonal antibodies target novel epitopes requiring both Lassa virus glycoprotein subunits

…, RB Wilson, CT Happi, PC Sabeti, SM Gevao… - Nature …, 2016 - nature.com
Lassa fever is a severe multisystem disease that often has haemorrhagic manifestations. The
epitopes of the Lassa virus (LASV) surface glycoproteins recognized by naturally infected …

Effects of mutations in the human uncoupling protein 3 gene on the respiratory quotient and fat oxidation in severe obesity and type 2 diabetes.

…, J Zhu, Y He, M Reitman, SM Gevao… - The Journal of …, 1998 - Am Soc Clin Investig
Human uncoupling protein 3 (UCP3) is a mitochondrial transmembrane carrier that uncouples
oxidative ATP phosphorylation. With the capacity to participate in thermogenesis and …

Evaluation of convalescent whole blood for treating Ebola Virus Disease in Freetown, Sierra Leone

…, P Kamara, A Goba, JBW Russell, SM Gevao - Journal of Infection, 2017 - Elsevier
Background Convalescent blood therapy has been a promising form of treatment for Ebola
Virus Disease (EVD), but less attention has been focused on it for treatment. Method We …

[HTML][HTML] Ebola virus antibody decay–stimulation in a high proportion of survivors

…, HA Doughty, J van Griensven, PW Horby, SM Gevao… - Nature, 2021 - nature.com
Neutralizing antibody function provides a foundation for the efficacy of vaccines and therapies
1 , 2 – 3 . Here, using a robust in vitro Ebola virus (EBOV) pseudo-particle infection assay …

An outbreak of Ebola virus disease in the Lassa fever zone

…, M Vandi, M Gbetuwa, SM Gevao… - The Journal of …, 2016 - academic.oup.com
Background. Kenema Government Hospital (KGH) has developed an advanced clinical and
laboratory research capacity to manage the threat of Lassa fever, a viral hemorrhagic fever (…

Sero-prevalence of hepatitis B virus among middle to high socio-economic antenatal population in Sierra Leone

IM Wurie, AT Wurie, SM Gevao - West African Journal of Medicine, 2005 - ajol.info
This study was designed in order to find out the prevalence of HBV markers amongst
pregnant women of middle and high socio-economic class in Sierra Leone. The aim was to …