User profiles for S. Moreno-Gamez

Stefany Moreno-Gámez

Massachusetts Institute of Technology
Verified email at mit.edu
Cited by 497

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

S Moreno-Gamez, AL Hill… - Proceedings of the …, 2015 - National Acad Sciences
Infections with rapidly evolving pathogens are often treated using combinations of drugs with
different mechanisms of action. One of the major goal of combination therapy is to reduce …

Trade-Offs predicted by metabolic network structure give rise to evolutionary specialization and phenotypic diversification

DM Ekkers, S Tusso, S Moreno-Gamez… - Molecular biology …, 2022 - academic.oup.com
Mitigating trade-offs between different resource-utilization functions is key to an organism’s
ecological and evolutionary success. These trade-offs often reflect metabolic constraints with …

How bacteria navigate varying environments

S Moreno-Gámez - Science, 2022 - science.org
A key to the impressive success of bacteria in nature is their ability to adapt to new
environments. Owing to their short generation times, these adaptations often result from genetic …

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multi-drug resistance

S Moreno-Gamez, AL Hill, DIS Rosenbloom, DA Petrov… - bioRxiv, 2014 - biorxiv.org
Infections with rapidly evolving pathogens are often treated using combinations of drugs with
different mechanisms of action. One of the major goals of combination therapy is to reduce …

[PDF][PDF] On the origin and function of phenotypic variation in bacteria

S Moreno Gamez - research.rug.nl
… of Groningen On the origin and function of phenotypic variation in bacteria Moreno Gamez,
Stefany … On the origin and function of phenotypic variation in bacteria Moreno Gamez, Stefany …

On the origin and function of phenotypic variation in bacteria

SM Gamez - 2020 - research.rug.nl
… of Groningen On the origin and function of phenotypic variation in bacteria Moreno Gamez,
Stefany … On the origin and function of phenotypic variation in bacteria Moreno Gamez, Stefany …

[CITATION][C] Research Report 2: CSP production and its pivotal role in pneumococcal competence development

S Moreno-Gamez, S van Doorn, JW Veening… - 2013 - fse.studenttheses.ub.rug.nl
Moreno-Gamez, S. and van Doorn, S. and Veening, JW and Weissing, FJ and Sorg, R.
and Kjos, M. … Student Theses Faculty of Science and Engineering is powered by EPrints 3 …

[CITATION][C] Research Report 1: The role of drug penetration in the evolution of resistance to combination therapy

S Moreno-Gamez, A Hill, D Rosenbloom, P Pennings… - 2013 - fse.studenttheses.ub.rug.nl
Moreno-Gamez, S and Hill, A and Rosenbloom, D and Pennings, P and Nowak, M (2013)
Research Report 1 : The role of drug penetration in the evolution of resistance to combination …

[PDF][PDF] Antibiotic-induced cell chaining triggers pneumococcal competence by reshaping quorum sensing to autocrine-like signaling

A Domenech, J Slager, JW Veening - Cell reports, 2018 - cell.com
Streptococcus pneumoniae can acquire antibiotic resistance by activation of competence and
subsequent DNA uptake. Here, we demonstrate that aztreonam (ATM) and clavulanic acid …

[CITATION][C] Quorum sensing integrates environmental cues, cell density and cell history to control bacterial competence. Nat Commun 8: 854

S Moreno-Gamez, RA Sorg, A Domenech, M Kjos… - 2017