User profiles for S. Rodriguez-Perales
 | Sandra Rodriguez-PeralesStaff Scientist, CNIO Verified email at cnio.es Cited by 4341 |
[HTML][HTML] A faecal microbiota signature with high specificity for pancreatic cancer
… s, annealing at 65C for 20 s, extension at 72C for 30 s and a final extension at 72C for 10
min. This was followed by a size-selective cleanup using SPRIselect magnetic beads (0.8 left-…
min. This was followed by a size-selective cleanup using SPRIselect magnetic beads (0.8 left-…
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Secreted extracellular vesicles (EVs) influence the tumor microenvironment and promote distal
metastasis. Here we analyzed the involvement of melanoma-secreted EVs in lymph node …
metastasis. Here we analyzed the involvement of melanoma-secreted EVs in lymph node …
[HTML][HTML] Engineering human tumour-associated chromosomal translocations with the RNA-guided CRISPR–Cas9 system
…, JC Ramirez, S Rodriguez-Perales - Nature …, 2014 - nature.com
Cancer-related human chromosomal translocations are generated through the illegitimate
joining of two non-homologous chromosomes affected by double-strand breaks (DSB). …
joining of two non-homologous chromosomes affected by double-strand breaks (DSB). …
Immune profiling and quantitative analysis decipher the clinical role of immune-checkpoint expression in the tumor immune microenvironment of DLBCL
…, B Xu, N Hoe, S Rodríguez-Perales… - Cancer immunology …, 2019 - AACR
PD-1/L1 and CTLA-4 blockade immunotherapies have been approved for 13 types of
cancers and are being studied in diffuse large B-cell lymphoma (DLBCL), the most common …
cancers and are being studied in diffuse large B-cell lymphoma (DLBCL), the most common …
Differential Gene Expression Profile in Endometrioid and Nonendometrioid Endometrial Carcinoma: STK15 Is Frequently Overexpressed and Amplified …
…, C Sánchez-Estévez, R Cassia, S Rodríguez-Perales… - Cancer research, 2003 - AACR
Endometrial carcinoma (EC) comprises at least two types of cancer: endometrioid carcinomas
(EECs) are estrogen-related tumors, which are frequently euploid and have a good …
(EECs) are estrogen-related tumors, which are frequently euploid and have a good …
Gain-of-function mutations in DNMT3A in patients with paraganglioma
…, A Percesepe, M Falcioni, S Rodríguez-Perales… - Genetics in …, 2018 - nature.com
Purpose The high percentage of patients carrying germline mutations makes
pheochromocytomas/paragangliomas the most heritable of all tumors. However, there are still cases …
pheochromocytomas/paragangliomas the most heritable of all tumors. However, there are still cases …
[HTML][HTML] Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres
S Espejel, S Franco, S Rodríguez‐Perales… - The EMBO …, 2002 - embopress.org
… Ku86 is directly or indirectly impairing telomerase‐mediated telomere elongation. Hence,
Ku86 is one of the first negative regulators of telomerase‐mediated telomere elongation that is …
Ku86 is one of the first negative regulators of telomerase‐mediated telomere elongation that is …
[HTML][HTML] MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas
Temozolomide (TMZ) is an oral alkylating agent used for the treatment of glioblastoma and
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
is now becoming a chemotherapeutic option in patients diagnosed with high-risk low-grade …
[PDF][PDF] NHEJ-mediated repair of CRISPR-Cas9-induced DNA breaks efficiently corrects mutations in HSPCs from patients with fanconi anemia
…, H Hanenberg, J Sevilla, S Rodríguez-Perales… - Cell Stem Cell, 2019 - cell.com
Non-homologous end-joining (NHEJ) is the preferred mechanism used by hematopoietic
stem cells (HSCs) to repair double-stranded DNA breaks and is particularly increased in cells …
stem cells (HSCs) to repair double-stranded DNA breaks and is particularly increased in cells …
Cyclin D1 gene (CCND1) mutations in endometrial cancer
G Moreno-Bueno, S Rodríguez-Perales… - Oncogene, 2003 - nature.com
Cyclin D1 is frequently overexpressed in human neoplasias by gene rearrangement and
amplification, but no mutations in the CCND1 gene have so far been reported. However, in vitro …
amplification, but no mutations in the CCND1 gene have so far been reported. However, in vitro …