Antiretroviral-therapy rollout in resource-poor countries is often associated with limited, if any,
HIV-RNA monitoring. The effect of variable monitoring on the emergence of resistance …

HIV-1 comprises three groups, the main (M group), O (outlier) and N (non-M, non-O). The M
group, divided into 11 subtypes, is responsible for the global HIV-1 pandemic. …

Background Assessing the burden of COVID-19 on the basis of medically attended case
numbers is suboptimal given its reliance on testing strategy, changing case definitions, and …

Background The replication-competent recombinant vesicular stomatitis virus (rVSV)–based
vaccine expressing a Zaire ebolavirus (ZEBOV) glycoprotein was selected for rapid safety …

The infection fatality risk (IFR) is the average number of deaths per infection by a pathogen
and is key to characterising the severity of infection across the population and for specific …

… possibility that more-complex patterns are transmitted but that certain mutations are not
frequently identified in antiretroviral-naive patients because of reversion and the resistance test’s …

Background Resistance of HIV-1 to antiretroviral drugs is the main cause of antiretroviral-treatment
failure. We assessed the transmission of drug-resistant variants among individuals …

We investigated CD4 + and CD8 + T cell turnover in both healthy and HIV-1–infected adults
by measuring the nuclear antigen Ki-67 specific for cell proliferation. The mean growth …

… Injections were given intramuscularly over 30 s into the deltoid. … Arthritis was confirmed if
the study team noted swelling or if imaging showed joint effusion(s), or both. Participants with …

To assess the relation between resistance to antiretroviral drugs for treatment of HIV-1
infection and virological response to therapy, results from 12 different studies were re-analysed …