User profiles for Sergei Ryazansky

Sergei Ryazansky

Institute of Molecular Genetics
Verified email at img.ras.ru
Cited by 1338

[HTML][HTML] Euchromatic Transposon Insertions Trigger Production of Novel Pi- and Endo-siRNAs at the Target Sites in the Drosophila Germline

S Shpiz, S Ryazansky, I Olovnikov, Y Abramov… - PLoS …, 2014 - journals.plos.org
The control of transposable element (TE) activity in germ cells provides genome integrity
over generations. A distinct small RNA–mediated pathway utilizing Piwi-interacting RNAs (…

[HTML][HTML] Programmable RNA targeting by bacterial Argonaute nucleases with unconventional guide binding and cleavage specificity

…, A Olina, E Kropocheva, S Ryazansky… - Nature …, 2022 - nature.com
Argonaute proteins are programmable nucleases that have defense and regulatory
functions in both eukaryotes and prokaryotes. All known prokaryotic Argonautes (pAgos) …

DNA targeting and interference by a bacterial Argonaute nuclease

…, A Kudinova, O Maslova, M Ninova, S Ryazansky… - Nature, 2020 - nature.com
Members of the conserved Argonaute protein family use small RNA guides to locate their
mRNA targets and regulate gene expression and suppress mobile genetic elements in …

The expanded universe of prokaryotic Argonaute proteins

S Ryazansky, A Kulbachinskiy, AA Aravin - MBio, 2018 - Am Soc Microbiol
Members of the ancient family of Argonaute (Ago) proteins are present in all domains of life.
The common feature of Ago proteins is the ability to bind small nucleic acid guides and use …

Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea

A Kuzmenko, D Yudin, S Ryazansky… - Nucleic acids …, 2019 - academic.oup.com
Argonaute (Ago) proteins are key players in RNA interference in eukaryotes, where they
function as RNA-guided RNA endonucleases. Prokaryotic Argonautes (pAgos) are much more …

De novo piRNA cluster formation in the Drosophila germ line triggered by transgenes containing a transcribed transposon fragment

I Olovnikov, S Ryazansky, S Shpiz… - Nucleic acids …, 2013 - academic.oup.com
PIWI-interacting RNAs (piRNAs) provide defence against transposable element (TE) expansion
in the germ line of metazoans. piRNAs are processed from the transcripts encoded by …

[HTML][HTML] Evidence for post-transcriptional regulation of clustered microRNAs in Drosophila

SS Ryazansky, VA Gvozdev, E Berezikov - BMC genomics, 2011 - Springer
Background MicroRNAs (miRNA) are short 21-23nt RNAs capable of inhibiting translation of
complementary target messenger RNAs. Almost half of D. melanogaster miRNA genes are …

A novel organelle, the piNG-body, in the nuage of Drosophila male germ cells is associated with piRNA-mediated gene silencing

MV Kibanov, KS Egorova, SS Ryazansky… - Molecular biology of …, 2011 - Am Soc Cell Biol
Proteins of the PIWI subfamily Aub and AGO3 associated with the germline-specific perinuclear
granules (nuage) are involved in the silencing of retrotransposons and other selfish …

[HTML][HTML] Key role of piRNAs in telomeric chromatin maintenance and telomere nuclear positioning in Drosophila germline

E Radion, V Morgunova, S Ryazansky… - Epigenetics & …, 2018 - Springer
Background Telomeric small RNAs related to PIWI-interacting RNAs (piRNAs) have been
described in various eukaryotes; however, their role in germline-specific telomere function …

[HTML][HTML] The chromosome-scale genome assembly for the West Nile vector Culex quinquefasciatus uncovers patterns of genome evolution in mosquitoes

SS Ryazansky, C Chen, M Potters, AN Naumenko… - BMC biology, 2024 - Springer
Background Understanding genome organization and evolution is important for species
involved in transmission of human diseases, such as mosquitoes. Anophelinae and Culicinae …