Architecture and subunit arrangement of native AMPA receptors elucidated by cryo-EM
Glutamate-gated AMPA receptors mediate the fast component of excitatory signal transduction
at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are …
at chemical synapses throughout all regions of the mammalian brain. AMPA receptors are …
[PDF][PDF] Activation and desensitization mechanism of AMPA receptor-TARP complex by cryo-EM
AMPA receptors mediate fast excitatory neurotransmission in the mammalian brain and
transduce the binding of presynaptically released glutamate to the opening of a transmembrane …
transduce the binding of presynaptically released glutamate to the opening of a transmembrane …
Carbon catabolite repression of the maltose transporter revealed by X-ray crystallography
Efficient carbon utilization is critical to the survival of microorganisms in competitive environments.
To optimize energy usage, bacteria have developed an integrated control system to …
To optimize energy usage, bacteria have developed an integrated control system to …
Architecture of fully occupied GluA2 AMPA receptor–TARP complex elucidated by cryo-EM
Fast excitatory neurotransmission in the mammalian central nervous system is largely carried
out by AMPA-sensitive ionotropic glutamate receptors 1 . Localized within the postsynaptic …
out by AMPA-sensitive ionotropic glutamate receptors 1 . Localized within the postsynaptic …
Structural basis for substrate specificity in the Escherichia coli maltose transport system
ATP-binding cassette (ABC) transporters are molecular pumps that harness the chemical
energy of ATP hydrolysis to translocate solutes across the membrane. The substrates …
energy of ATP hydrolysis to translocate solutes across the membrane. The substrates …
Structure and mechanism of AMPA receptor—auxiliary protein complexes
S Chen, E Gouaux - Current opinion in structural biology, 2019 - Elsevier
… Author links open overlay panel Shanshuang Chen 1 , Eric Gouaux 1 2 … Chen, Y.
Kawasaki, RS Petralia, RJ Wenthold, RA Nicoll, DS Bredt … Chen …
Kawasaki, RS Petralia, RJ Wenthold, RA Nicoll, DS Bredt … Chen …
C-type inactivation and proton modulation mechanisms of the TASK3 channel
…, J Li, Q Zhang, H Yang, S Chen - Proceedings of the …, 2024 - National Acad Sciences
The TWIK-related acid-sensitive K + channel 3 (TASK3) belongs to the two-pore domain (K2P)
potassium channel family, which regulates cell excitability by mediating a constitutive “…
potassium channel family, which regulates cell excitability by mediating a constitutive “…
Assembly mechanisms of the neuronal gap junction channel connexin 36 elucidated by Cryo-EM
W Mao, S Chen - Archives of Biochemistry and Biophysics, 2024 - Elsevier
Electrical synapses are essential components of neural circuits. Neuronal signal transduction
across electrical synapses is primarily mediated by gap junction channels composed of …
across electrical synapses is primarily mediated by gap junction channels composed of …
Assembly and Cation-selectivity Mechanisms of Neuronal Gap Junction Channel Connexin 36 Elucidated by Cryo-EM
W Mao, S Chen - bioRxiv, 2023 - biorxiv.org
Electrical synapses are essential components of neural circuits. Dysfunction of electrical
synapses can lead to obstacles in learning and memory. Neural signal transduction across …
synapses can lead to obstacles in learning and memory. Neural signal transduction across …
[PDF][PDF] Activation and Desensitization Mechanism of AMPA Receptor-TARP Complex by Cryo-EM
S Chen, Y Zhao, Y Wang, M Shekhar, E Tajkhorshid… - Biophysical …, 2018 - cell.com
The majority of fast excitatory neurotransmission in mammalian synapses is initiated by α-amino-3-hydroxy-5-methyl-4-isoxazole
propionic acid (AMPA) receptors, receptors which …
propionic acid (AMPA) receptors, receptors which …