Primary cilia are specialised sensory and developmental signalling devices extending from
the surface of most eukaryotic cells. Defects in these organelles cause inherited human …

Primary cilia are microtubule-based sensory organelles whose structures and functions must
be actively maintained throughout animal lifespan to support signal transduction pathways …

The distinction between non‐associative and associative forms of learning has historically
been based on the behavioral training paradigm. Through discovering the molecular …

We investigated the role of the Caenorhabditis elegans CREB (cAMP response element
binding protein) homologue, crh-1, in response to tap (nonlocalized mechanosensory …

Habituation is a ubiquitous form of non-associative learning observed as a decrement in
responding to repeated stimulation that cannot be explained by sensory adaptation or motor …

The ability to learn and remember is critical for all animals to survive in the ever-changing
environment. As we age, many of our biological faculties decay and of these, decline in …

Sociality is widespread in caterpillars, but the communication mechanisms used for group
formation and cohesion are poorly understood. Here, we present the first evidence that …

Lasting memories are likely to result from a lasting change in neurotransmission. In the
nematode Caenorhabditis elegans, spaced training with a tap stimulus induces habituation to the …

10.7554/eLife.37271.001 Neurons throughout the mammalian brain possess non-motile cilia,
organelles with varied functions in sensory physiology and cellular signaling. Yet, the roles …

The conserved Shugoshin (SGO) protein family is essential for mediating proper chromosome
segregation from yeast to humans but has also been implicated in diverse roles outside of …