Over 2 billion people worldwide are infected with helminths (worms). Similarly, infection with
Mycobacterium tuberculosis (Mtb) occurs in over a third of the world's population, often with …

Strongyloides stercoralis is an intestinal nematode of humans that infects tens of millions of
people worldwide. S. stercoralis is unique among intestinal nematodes in its ability to …

The precise function of eosinophils in parasitic infection in vivo remains poorly understood
despite eosinophils having been shown to be potent effectors in killing parasites in vitro. …

Parasitic nematodes that cause elephantiasis and river blindness threaten hundreds of
millions of people in the developing world. We have sequenced the ∼90 megabase (Mb) …

… TB Nutman is a stockholder in Johnson & Johnson and is employed by the National Institutes
of Health. J. Ring has received research support from Novartis, Schering-Plough, Fujisawa…

CC-chemokine receptor (CCR) 6 is the only known receptor for macrophage inflammatory
protein (MIP)-3α, a CC chemokine chemotactic for lymphocytes and dendritic cells. Using anti-…

Background CC chemokine receptor 5 (CCR5) is a cell entry cofactor for macrophage-tropic
isolates of human immunodeficiency virus-1 (HIV-1). Recently, an inactive CCR5 allele (…

How the immune system adapts to malnutrition to sustain immunity at barrier surfaces, such
as the intestine, remains unclear. Vitamin A deficiency is one of the most common …

… Before in vitro infection, cryopreserved M tuberculosis aliquots were thawed and suspended
in culture medium by vortexing briefly. M tuberculosis bacilli were sonicated to disrupt small …

Background: Childhood infections might protect against the expression of atopy. Geohelminths
are among the most prevalent infections of childhood and might contribute to the low …