Stochasticity pervades life at the cellular level. Cells receive stochastic signals, perform
detection and transduction with stochastic biochemistry, and grow and die in stochastic …

… Theodore Perkins was also supported by a graduate fellowship from the University of …
TJ Perkins and AG Barto. Heuristic search in infinite state spaces guided by Lyapunov …

A fundamental problem in functional genomics is to determine the structure and dynamics of
genetic networks based on expression data. We describe a new strategy for solving this …

Pax3 and Pax7 regulate stem cell function in skeletal myogenesis. However, molecular insight
into their distinct roles has remained elusive. Using gene expression data combined with …

Background In spite of extensive research on the effect of mutation and selection on codon
usage, a general model of codon usage bias due to mutational bias has been lacking. …

Declining real cereal prices, increased input costs and increased awareness of the environment
are likely to necessitate making spraying decisions on the basis of economic thresholds. …

Background Neurons require highly specialized intracellular membrane trafficking, especially
at synapses. Rab GTPases are considered master regulators of membrane trafficking in all …

T-cell acute lymphoblastic leukemia (T-ALL) is a heterogeneous group of hematological
tumors composed of distinct subtypes that vary in their genetic abnormalities, gene expression …

Dynamic cellular processes such as differentiation are driven by changes in the abundances
of transcription factors (TFs). However, despite years of studies, our knowledge about the …

EGFRvIII-STAT3 signaling is important in glioblastoma pathogenesis. Here, we identified the
cytokine receptor OSMR as a direct target gene of the transcription factor STAT3 in mouse …