Background Colorectal cancer screening programmes and uptake vary substantially across
Europe. We aimed to compare changes over time in colorectal cancer incidence, mortality, …

… Precursor B-cell or T-cell lymphoblastic leukaemia or lymphoma (and Burkitt's leukaemia or
… Other T-cell lymphomas and natural killer cell neoplasms 0·62 0·60–0·63 9656 3128 39·0% …

Objective The purpose of this study was to identify genetic variants underlying the considerable
individual differences in response to antidepressant treatment. The authors performed a …

… Innate immunity cells serve as a bridge to adaptive immunity cells including T helper 1
cells, cytotoxic T cells and resident memory T cells. IFN-γ is the primary cytokine mediator that …

… NSEM = 1 N t N s ∑ i = 1 N s SD ( i ) X ( i ) · 100 % , where SD(i) and X ( i ) are the standard
deviation and the mean of the ith subject, respectively, with N t being the number of trials (N t …

Breast cancer treatments have evolved over the past decades, although several widely used
treatments have adverse cardiac effects. Radiotherapy generally improves the survival of …

Background An increasing proportion of colorectal cancers (CRCs) are detected through
screening due to the availability of organised population-based programmes. We aimed to …

PR, and HER2 by immunohistochemistry (IHC), TNBC comprises approximately 15% of
incident breast cancers and is over-represented among those with metastatic disease. 2–4 …

… T < (0.0001, 0.001, 0.05, 0.1, 0.2, 0.3, 0.4, 0.5, 1) were used with all pruned SNPs included
in the final threshold P T … correlation between PRS at 9 P T values, and then corrected further …

Background Results of intervention studies in patients with type 2 diabetes have led to
concerns about the safety of aiming for normal blood glucose concentrations. We assessed …