A guided tour of the Trans‐Proteomic Pipeline
The Trans‐Proteomic Pipeline (TPP) is a suite of software tools for the analysis of MS/MS
data sets. The tools encompass most of the steps in a proteomic data analysis workflow in a …
data sets. The tools encompass most of the steps in a proteomic data analysis workflow in a …
ProteomeXchange provides globally coordinated proteomics data submission and dissemination
Individual resources can join ProteomeXchange by implementing the ProteomeXchange
data submission and dissemination guidelines, and metadata requirements. In the current …
data submission and dissemination guidelines, and metadata requirements. In the current …
Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
…, RR Splett, FA Fletcher, E Maraskovsky, T Farrah… - Cell, 1993 - cell.com
Cloning of a ligand for the murine flt3/flk-2 tyrosine kinase receptor was undertaken using a
soluble form of the receptor to identify a source of ligand. A murine T cell line, P750. 3A4, …
soluble form of the receptor to identify a source of ligand. A murine T cell line, P750. 3A4, …
[HTML][HTML] The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons
Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as
major risk factors for its development. Cardiovascular disease is the leading cause of death …
major risk factors for its development. Cardiovascular disease is the leading cause of death …
CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF
CA Smith, HJ Gruss, T Davis, D Anderson, T Farrah… - Cell, 1993 - cell.com
… murine T … T cell cDNA library yielded the human homolog, which is 72% identical at the
amino acid level. The recombinant human ligand enhances the proliferation of CD3‘activated T …
amino acid level. The recombinant human ligand enhances the proliferation of CD3‘activated T …
Established and emerging therapeutic uses of PDE type 5 inhibitors in cardiovascular disease
N Tzoumas, TE Farrah, N Dhaun… - British Journal of …, 2020 - Wiley Online Library
… Sildenafil, udenafil, vardenafil and avanafil have similar T max values and thus comparable
… In comparison, mirodenafil and lodenafil have slightly higher T max values, with limited …
… In comparison, mirodenafil and lodenafil have slightly higher T max values, with limited …
Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor
…, E Baker, GR Sutherland, KH Grabstein, T Farrah… - Cell, 1993 - cell.com
… CD27 is a surface antigen found on T and B ceils that has … T ceils and enhances the
generation of cytoiytic T ceils. … to CD3etimulated peripheral blood T ceils and T cell clones was …
generation of cytoiytic T ceils. … to CD3etimulated peripheral blood T ceils and T cell clones was …
High-throughput generation of selected reaction-monitoring assays for proteins and proteomes
Selected reaction monitoring (SRM) uses sensitive and specific mass spectrometric assays
to measure target analytes across multiple samples, but it has not been broadly applied in …
to measure target analytes across multiple samples, but it has not been broadly applied in …
[HTML][HTML] A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas
T Farrah, EW Deutsch, GS Omenn, DS Campbell… - Molecular & cellular …, 2011 - ASBMB
Human blood plasma can be obtained relatively noninvasively and contains proteins from
most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma …
most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma …
Parent-of-origin-specific signatures of de novo mutations
… Overall, the nucleotide substitution frequencies for DNMs were dominated by C–T and T–C
changes, giving rise to a transition/transversion ratio (Ts/Tv) of 2.23. Haplotype assembly of …
changes, giving rise to a transition/transversion ratio (Ts/Tv) of 2.23. Haplotype assembly of …