A guided tour of the Trans‐Proteomic Pipeline

EW Deutsch, L Mendoza, D Shteynberg, T Farrah… - …, 2010 - Wiley Online Library
The Trans‐Proteomic Pipeline (TPP) is a suite of software tools for the analysis of MS/MS
data sets. The tools encompass most of the steps in a proteomic data analysis workflow in a …

ProteomeXchange provides globally coordinated proteomics data submission and dissemination

…, F Reisinger, D Ríos, JA Dianes, Z Sun, T Farrah… - Nature …, 2014 - nature.com
Individual resources can join ProteomeXchange by implementing the ProteomeXchange
data submission and dissemination guidelines, and metadata requirements. In the current …

Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells

…, RR Splett, FA Fletcher, E Maraskovsky, T Farrah… - Cell, 1993 - cell.com
Cloning of a ligand for the murine flt3/flk-2 tyrosine kinase receptor was undertaken using a
soluble form of the receptor to identify a source of ligand. A murine T cell line, P750. 3A4, …

[HTML][HTML] The eye, the kidney, and cardiovascular disease: old concepts, better tools, and new horizons

TE Farrah, B Dhillon, PA Keane, DJ Webb, N Dhaun - Kidney international, 2020 - Elsevier
Chronic kidney disease (CKD) is common, with hypertension and diabetes mellitus acting as
major risk factors for its development. Cardiovascular disease is the leading cause of death …

CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF

CA Smith, HJ Gruss, T Davis, D Anderson, T Farrah… - Cell, 1993 - cell.com
… murine TT cell cDNA library yielded the human homolog, which is 72% identical at the
amino acid level. The recombinant human ligand enhances the proliferation of CD3‘activated T

Established and emerging therapeutic uses of PDE type 5 inhibitors in cardiovascular disease

N Tzoumas, TE Farrah, N Dhaun… - British Journal of …, 2020 - Wiley Online Library
… Sildenafil, udenafil, vardenafil and avanafil have similar T max values and thus comparable
… In comparison, mirodenafil and lodenafil have slightly higher T max values, with limited …

Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor

…, E Baker, GR Sutherland, KH Grabstein, T Farrah… - Cell, 1993 - cell.com
… CD27 is a surface antigen found on T and B ceils that has … T ceils and enhances the
generation of cytoiytic T ceils. … to CD3etimulated peripheral blood T ceils and T cell clones was …

High-throughput generation of selected reaction-monitoring assays for proteins and proteomes

P Picotti, O Rinner, R Stallmach, F Dautel, T Farrah… - Nature …, 2010 - nature.com
Selected reaction monitoring (SRM) uses sensitive and specific mass spectrometric assays
to measure target analytes across multiple samples, but it has not been broadly applied in …

[HTML][HTML] A high-confidence human plasma proteome reference set with estimated concentrations in PeptideAtlas

T Farrah, EW Deutsch, GS Omenn, DS Campbell… - Molecular & cellular …, 2011 - ASBMB
Human blood plasma can be obtained relatively noninvasively and contains proteins from
most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma …

Parent-of-origin-specific signatures of de novo mutations

JM Goldmann, WSW Wong, M Pinelli, T Farrah… - Nature …, 2016 - nature.com
… Overall, the nucleotide substitution frequencies for DNMs were dominated by C–T and T–C
changes, giving rise to a transition/transversion ratio (Ts/Tv) of 2.23. Haplotype assembly of …