The genetic structure of the indigenous hunter-gatherer peoples of southern Africa, the oldest
known lineage of modern human, is important for understanding human diversity. Studies …

We assembled genome-wide data from 16 prehistoric Africans. We show that the anciently
divergent lineage that comprises the primary ancestry of the southern African San had a …

Background Using visual, biological, and electronic health records data as the sole input
source, pretrained convolutional neural networks and conventional machine learning methods …

Somatic structural variants (SVs), which are variants that typically impact >50 nucleotides,
play a significant role in cancer development and evolution but are notoriously more difficult to …

The Tasmanian devil (Sarcophilus harrisii) is threatened with extinction because of a
contagious cancer known as Devil Facial Tumor Disease. The inability to mount an immune …

Fusion genes are a major cause of cancer. Their rapid and accurate diagnosis can inform
clinical action, but current molecular diagnostic assays are restricted in resolution and …

Anatomically modern humans originated in Africa around 200 thousand years ago (ka) 1, 2,
3, 4. Although some of the oldest skeletal remains suggest an eastern African origin 2, …

Heparin-induced thrombocytopenia (HIT) is a life- and limb-threatening thrombotic disorder
that develops after exposure to heparin, often in the setting of inflammation. We have shown …

Statement: In naming population groups, we think a chief aim is to use terms that the group
members use themselves, or find familiar and comfortable. The terms used in this manuscript …

Within-population genetic diversity is greatest within Africa, while between-population genetic
diversity is directly proportional to geographic distance. The most divergent contemporary …