Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery

…, D Brambilla, N Mackiewicz, P Couvreur - Chemical Society …, 2013 - pubs.rsc.org
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …

Stimuli-responsive nanocarriers for drug delivery

S Mura, J Nicolas, P Couvreur - Nature materials, 2013 - nature.com
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive
devices that deliver a drug in spatial-, temporal- and dosage-controlled fashions have become …

Nanoparticles in cancer therapy and diagnosis

I Brigger, C Dubernet, P Couvreur - Advanced drug delivery reviews, 2012 - Elsevier
Numerous investigations have shown that both tissue and cell distribution profiles of
anticancer drugs can be controlled by their entrapment in submicronic colloidal systems (…

Porous metal–organic-framework nanoscale carriers as a potential platform for drug delivery and imaging

…, PN Bories, L Cynober, S Gil, G Férey, P Couvreur… - Nature materials, 2010 - nature.com
In the domain of health, one important challenge is the efficient delivery of drugs in the body
using non-toxic nanocarriers. Most of the existing carrier materials show poor drug loading (…

Metal–organic frameworks in biomedicine

…, R Gref, T Baati, PK Allan, G Maurin, P Couvreur… - Chemical …, 2012 - ACS Publications
1.1. Influence of the Composition Coordination polymers or MOFs (metalÀorganic frameworks)
are the latest class of ordered porous solids. 1À5Since their discovery in 1989 by Robson…

Magnetic nanoparticles: design and characterization, toxicity and biocompatibility, pharmaceutical and biomedical applications

LH Reddy, JL Arias, J Nicolas, P Couvreur - Chemical reviews, 2012 - ACS Publications
In recent years, considerable efforts have been spent in the development of magnetic
nanoparticles (MNPs), the understanding of their behavior, and the improvement of their …

Nanocarriers' entry into the cell: relevance to drug delivery

H Hillaireau, P Couvreur - Cellular and molecular life sciences, 2009 - Springer
Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …

BioMOFs: metal–organic frameworks for biological and medical applications

…, G Férey, R Gref, P Couvreur… - Angewandte Chemie …, 2010 - Wiley Online Library
The class of highly porous materials called metal–organic frameworks offer many opportunities
for applications across biology and medicine. Their wide range of chemical composition …

Nanotechnology: intelligent design to treat complex disease

P Couvreur, C Vauthier - Pharmaceutical research, 2006 - Springer
The purpose of this expert review is to discuss the impact of nanotechnology in the treatment
of the major health threats including cancer, infections, metabolic diseases, autoimmune …

Adjuvant radiotherapy and 5-fluorouracil after curative resection of cancer of the pancreas and periampullary region: phase III trial of the EORTC gastrointestinal tract …

…, J Jeekel, T Sahmoud, R van Pel, ML Couvreur… - Annals of …, 1999 - journals.lww.com
Objective The survival benefit of adjuvant radiotherapy and 5-fluorouracil versus observation
alone after surgery was investigated in patients with pancreatic head and periampullary …