TSLP: an epithelial cell cytokine that regulates T cell differentiation by conditioning dendritic cell maturation

YJ Liu, V Soumelis, N Watanabe, T Ito… - Annu. Rev …, 2007 - annualreviews.org
Dendritic cells (DCs) are professional antigen-presenting cells that have the ability to sense
infection and tissue stress, sample and present antigen to T lymphocytes, and induce …

Dendritic cell lineage, plasticity and cross-regulation

YJ Liu, H Kanzler, V Soumelis, M Gilliet - Nature immunology, 2001 - nature.com
Dendritic cells (DCs) are professional antigen-presenting cells that have an extraordinary
capacity to stimulate naïve T cells and initiate primary immune responses. Here we review …

Hepatitis C: viral and host factors associated with non‐response to pegylated interferon plus ribavirin

…, M Vidaud, D Saadoun, V Soumelis… - Liver …, 2010 - Wiley Online Library
Abstract Treatment for chronic hepatitis C virus (HCV) infection has evolved considerably in
the last years. The standard of care (SOC) for HCV infection consists in the combination of …

Human epithelial cells trigger dendritic cell–mediated allergic inflammation by producing TSLP

V Soumelis, PA Reche, H Kanzler, W Yuan… - Nature …, 2002 - nature.com
Whether epithelial cells play a role in triggering the immune cascade leading to T helper 2 (T
H 2)-type allergic inflammation is not known. We show here that human thymic stromal …

Reciprocal control of T helper cell and dendritic cell differentiation

MC Rissoan, V Soumelis, N Kadowaki, G Grouard… - Science, 1999 - science.org
It is not known whether subsets of dendritic cells provide different cytokine microenvironments
that determine the differentiation of either type-1 T helper (T H 1) or T H 2 cells. Human …

Inborn errors of type I IFN immunity in patients with life-threatening COVID-19

…, MJ Ciancanelli, I Meyts, T Maniatis, V Soumelis… - Science, 2020 - science.org
INTRODUCTION Clinical outcomes of human severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) infection range from silent infection to lethal coronavirus disease 2019 (…

A critical function for transforming growth factor-β, interleukin 23 and proinflammatory cytokines in driving and modulating human TH-17 responses

…, SI Bogiatzi, P Hupé, E Barillot, V Soumelis - Nature …, 2008 - nature.com
Interleukin 17 (IL-17)–producing T helper 17 cells (T H -17 cells) have been described as a
T helper cell subset distinct from T helper type 1 (T H 1) and T H 2 cells, with specific …

[PDF][PDF] Fibroblast heterogeneity and immunosuppressive environment in human breast cancer

…, A Zinovyev, AM Givel, MC Parrini, V Soumelis… - Cancer cell, 2018 - cell.com
Carcinoma-associated fibroblasts (CAF) are key players in the tumor microenvironment.
Here, we characterize four CAF subsets in breast cancer with distinct properties and levels of …

[PDF][PDF] Human inflammatory dendritic cells induce Th17 cell differentiation

…, G Chiocchia, A Hosmalin, M Dalod, V Soumelis… - Immunity, 2013 - cell.com
Dendritic cells (DCs) are critical regulators of immune responses. Under noninflammatory
conditions, several human DC subsets have been identified. Little is known, however, about …

A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

…, T Buhl, A Ikoma, J Buddenkotte, V Soumelis… - Journal of allergy and …, 2014 - Elsevier
Background Although the cytokine IL-31 has been implicated in inflammatory and lymphoma-associated
itch, the cellular basis for its pruritic action is yet unclear. Objective We sought to …