Single nucleotide polymorphism (SNP) discovery and genotyping are essential to genetic
mapping. There remains a need for a simple, inexpensive platform that allows high-density …

… We are grateful to members of the Cresko Lab who have provided comments and encouragement
at the University of Oregon. This work has been generously supported by NSF grants …

… , the sequence reads can instead be aligned to one another, with SNPs identified and
zygosities scored for individuals in the same manner as we describe here (Hohenlohe and Cresko …

A whole genome duplication occurred in the ancestor of all salmonid fishes some 50–100
million years ago. Early inheritance studies with allozymes indicated that loci in the salmonid …

Restriction site associated DNA (RAD) tags are a genome-wide representation of every site
of a particular restriction enzyme by short DNA tags. Most organisms segregate large …

A promising route for understanding the origin and diversification of organismal form is
through studies at the intersection of evolution and development (evo-devo). While much has …

The distinction between model and nonmodel organisms is becoming increasingly blurred.
High-throughput, second-generation sequencing approaches are being applied to …

Next-generation sequencing technologies are revolutionizing the field of evolutionary biology,
opening the possibility for genetic analysis at scales not previously possible. Research in …

Most adaptation is thought to occur through the fixation of numerous alleles at many different
loci. Consequently, the independent evolution of similar phenotypes is predicted to occur …

… Hohenlohe PA, Bassham S., Etter PD, Stiffler N., Johnson EA& Cresko WA . 2010 Population
genomics of parallel adaptation in threespine stickleback using sequenced RAD tags. …