Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host
receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus …

The pathogenesis of chronic obstructive pulmonary disease (COPD) is based on the innate
and adaptive inflammatory immune response to the inhalation of toxic particles and gases. …

Compared with the effects of chronic smoke exposure on lung function and airway inflammation,
there are few data on the acute effects of smoking. A review of the literature identified …

Severe acute respiratory syndrome (SARS) is an acute infectious disease that spreads mainly
via the respiratory route. A distinct coronavirus (SARS‐CoV) has been identified as the …

Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype with poor prognosis 1 ,
2 , 3 . We sequenced 29 SCLC exomes, 2 genomes and 15 transcriptomes and found an …

Lung cancer remains one of the leading causes of cancer-related death in developed countries.
Although lung adenocarcinomas with EGFR mutations or EML4-ALK fusions respond to …

Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions. …

Background The use of multidetector computed tomography (CT) in lung-cancer screening
trials involving subjects with an increased risk of lung cancer has highlighted the problem for …

BACKGROUND Inflammatory changes in the airways in chronic obstructive pulmonary disease
(COPD) are largely attributed to smoking, yet they may be present even if patients do not …

Although genomically targeted therapies have improved outcomes for patients with lung
adenocarcinoma, little is known about the genomic alterations that drive squamous cell cancer (…