User profiles for X. C. Dopico
Xaquin Castro DopicoKarolinska Institutet Verified email at ki.se Cited by 1609 |
Drivers of infectious disease seasonality: potential implications for COVID-19
…, ES Schernhammer, XC Dopico… - Journal of biological …, 2021 - journals.sagepub.com
Not 1 year has passed since the emergence of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). Since its …
2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19). Since its …
[HTML][HTML] Widespread seasonal gene expression reveals annual differences in human immunity and physiology
Seasonal variations are rarely considered a contributing component to human tissue function
or health, although many diseases and physiological process display annual periodicities. …
or health, although many diseases and physiological process display annual periodicities. …
Neutralisation sensitivity of the SARS-CoV-2 omicron (B. 1.1. 529) variant: a cross-sectional study
Background The SARS-CoV-2 omicron (B.1.1.529) variant, which was first identified in
November, 2021, spread rapidly in many countries, with a spike protein highly diverged from …
November, 2021, spread rapidly in many countries, with a spike protein highly diverged from …
[HTML][HTML] IL-21 production by CD4+ effector T cells and frequency of circulating follicular helper T cells are increased in type 1 diabetes patients
…, HZ Simons, WS Thompson, AJ Cutler, XC Dopico… - Diabetologia, 2015 - Springer
Aims/hypothesis Type 1 diabetes results from the autoimmune destruction of insulin-secreting
pancreatic beta cells by T cells. Despite the established role of T cells in the pathogenesis …
pancreatic beta cells by T cells. Despite the established role of T cells in the pathogenesis …
[PDF][PDF] Immunoglobulin germline gene polymorphisms influence the function of SARS-CoV-2 neutralizing antibodies
…, A Nicoletto, DJ Sheward, H Das, XC Dopico… - Immunity, 2023 - cell.com
The human immunoglobulin heavy-chain (IGH) locus is exceptionally polymorphic, with high
levels of allelic and structural variation. Thus, germline IGH genotypes are personal, which …
levels of allelic and structural variation. Thus, germline IGH genotypes are personal, which …
Translation initiation of leaderless and polycistronic transcripts in mammalian mitochondria
The synthesis of mitochondrial OXPHOS complexes is central to cellular metabolism, yet many
molecular details of mitochondrial translation remain elusive. It has been commonly held …
molecular details of mitochondrial translation remain elusive. It has been commonly held …
[PDF][PDF] Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles
Definition of the specific germline immunoglobulin (Ig) alleles present in an individual is a
critical first step to delineate the ontogeny and evolution of antigen-specific antibody responses…
critical first step to delineate the ontogeny and evolution of antigen-specific antibody responses…
[PDF][PDF] SARS-CoV-2 protein subunit vaccination of mice and rhesus macaques elicits potent and durable neutralizing antibody responses
The outbreak and spread of SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2)
is a current global health emergency, and effective prophylactic vaccines are needed …
is a current global health emergency, and effective prophylactic vaccines are needed …
[HTML][HTML] Cells with Treg-specific FOXP3 demethylation but low CD25 are prevalent in autoimmunity
Identification of alterations in the cellular composition of the human immune system is key to
understanding the autoimmune process. Recently, a subset of FOXP3 + cells with low CD25 …
understanding the autoimmune process. Recently, a subset of FOXP3 + cells with low CD25 …
[HTML][HTML] Neonatal and adult recent thymic emigrants produce IL-8 and express complement receptors CR1 and CR2
The maintenance of peripheral naive T lymphocytes in humans is dependent on their
homeostatic division, not continuing emigration from the thymus, which undergoes involution with …
homeostatic division, not continuing emigration from the thymus, which undergoes involution with …