User profiles for Y. Loe-Mie
Yann Loe-MieInstitut Pasteur Verified email at pasteur.fr Cited by 2151 |
Two independent modes of chromatin organization revealed by cohesin removal
Imaging and chromosome conformation capture studies have revealed several layers of
chromosome organization, including segregation into megabase-sized active and inactive …
chromosome organization, including segregation into megabase-sized active and inactive …
[PDF][PDF] Cnidarian cell type diversity and regulation revealed by whole-organism single-cell RNA-Seq
…, F Plessier, MP Mailhé, J Renno, Y Loe-Mie… - Cell, 2018 - cell.com
The emergence and diversification of cell types is a leading factor in animal evolution. So far,
systematic characterization of the gene regulatory programs associated with cell type …
systematic characterization of the gene regulatory programs associated with cell type …
A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity
M Boulch, M Cazaux, Y Loe-Mie, R Thibaut… - Science …, 2021 - science.org
Chimeric antigen receptor (CAR) T cell therapy relies on the activity of a large pool of tumor-targeting
cytotoxic effectors. Whether CAR T cells act autonomously or require interactions …
cytotoxic effectors. Whether CAR T cells act autonomously or require interactions …
Fluorescent nanodiamond tracking reveals intraneuronal transport abnormalities induced by brain-disease-related genetic risk factors
… Using the Track Manager plugin, we exported a text file containing the spot (x,y) coordinates
and the signal amplitude and background (based on a 2D Gaussian fitting of fluorescence …
and the signal amplitude and background (based on a 2D Gaussian fitting of fluorescence …
DYRK1A interacts with the REST/NRSF-SWI/SNF chromatin remodelling complex to deregulate gene clusters involved in the neuronal phenotypic traits of Down …
The molecular mechanisms that lead to the cognitive defects characteristic of Down syndrome
(DS), the most frequent cause of mental retardation, have remained elusive. Here we use …
(DS), the most frequent cause of mental retardation, have remained elusive. Here we use …
SMARCA2 and other genome-wide supported schizophrenia-associated genes: regulation by REST/NRSF, network organization and primate-specific evolution
Y Loe-Mie, AM Lepagnol-Bestel… - Human molecular …, 2010 - academic.oup.com
The SMARCA2 gene, which encodes BRM in the SWI/SNF chromatin-remodeling complex,
was recently identified as being associated with schizophrenia (SZ) in a genome-wide …
was recently identified as being associated with schizophrenia (SZ) in a genome-wide …
Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism
…, AM Lepagnol-Bestel, F Tores, Y Loe-Mie… - Human molecular …, 2008 - academic.oup.com
Autism spectrum disorders (ASDs) are common, heritable, but genetically heterogeneous
neurodevelopmental conditions. We recently defined a susceptibility locus for ASDs on …
neurodevelopmental conditions. We recently defined a susceptibility locus for ASDs on …
[HTML][HTML] HENA, heterogeneous network-based data set for Alzheimer's disease
Alzheimer’s disease and other types of dementia are the top cause for disabilities in later
life and various types of experiments have been performed to understand the underlying …
life and various types of experiments have been performed to understand the underlying …
[PDF][PDF] Transient suppression of SUMOylation in embryonic stem cells generates embryo-like structures
Recent advances in synthetic embryology have opened new avenues for understanding the
complex events controlling mammalian peri-implantation development. Here, we show that …
complex events controlling mammalian peri-implantation development. Here, we show that …
[HTML][HTML] Single cell atlas of Xenoturbella bocki highlights limited cell-type complexity
Phylogenetic analyses over the last two decades have united a few small, and previously
orphan clades, the nematodermatids, acoels and xenoturbelids, into the phylum …
orphan clades, the nematodermatids, acoels and xenoturbelids, into the phylum …