User profiles for Z. H. Gumus
 | Zeynep H. GümüşMount Sinai School of Medicine, Weill Cornell Medical College Verified email at mssm.edu Cited by 9414 |
[PDF][PDF] Immunology of COVID-19: current state of the science
…, N Bhardwaj, BD Brown, B Greenbaum, ZH Gümüş… - Immunity, 2020 - cell.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an …
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting an …
[PDF][PDF] A proteogenomic portrait of lung squamous cell carcinoma
Lung squamous cell carcinoma (LSCC) remains a leading cause of cancer death with few
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …
therapeutic options. We characterized the proteogenomic landscape of LSCC, providing a …
[PDF][PDF] A microRNA miR-34a-regulated bimodal switch targets Notch in colon cancer stem cells
microRNAs regulate developmental cell-fate decisions, tissue homeostasis, and oncogenesis
in distinct ways relative to proteins. Here, we show that the tumor suppressor microRNA …
in distinct ways relative to proteins. Here, we show that the tumor suppressor microRNA …
[PDF][PDF] Integrated proteogenomic characterization across major histological types of pediatric brain cancer
We report a comprehensive proteogenomics analysis, including whole-genome sequencing,
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …
RNA sequencing, and proteomics and phosphoproteomics profiling, of 218 tumors across 7 …
[PDF][PDF] Proteogenomic data and resources for pan-cancer analysis
The National Cancer Institute's Clinical Proteomic Tumor Analysis Consortium (CPTAC)
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …
investigates tumors from a proteogenomic perspective, creating rich multi-omics datasets …
[HTML][HTML] SCLC: epidemiology, risk factors, genetic susceptibility, molecular pathology, screening, and early detection
We review research regarding the epidemiology, risk factors, genetic susceptibility, molecular
pathology, and early detection of SCLC, a deadly tumor that accounts for 14% of lung …
pathology, and early detection of SCLC, a deadly tumor that accounts for 14% of lung …
[BOOK][B] Handbook of test problems in local and global optimization
Significant research activities have taken place in the areas of local and global optimization
in the last two decades. Many new theoretical, computational, algorithmic, and software …
in the last two decades. Many new theoretical, computational, algorithmic, and software …
Gene expression elucidates functional impact of polygenic risk for schizophrenia
Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from dorsolateral …
confer liability is uncertain. The CommonMind Consortium sequenced RNA from dorsolateral …
Comprehensive functional genomic resource and integrative model for the human brain
INTRODUCTION Strong genetic associations have been found for a number of psychiatric
disorders. However, understanding the underlying molecular mechanisms remains …
disorders. However, understanding the underlying molecular mechanisms remains …
[PDF][PDF] Proteogenomic characterization reveals therapeutic vulnerabilities in lung adenocarcinoma
To explore the biology of lung adenocarcinoma (LUAD) and identify new therapeutic
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …
opportunities, we performed comprehensive proteogenomic characterization of 110 tumors and …