… dependency was calculated as the difference between a single cell line's dependency
score for a given gene and the mean score for that gene across all lines screened, then Z-score-…

Combinatorial genetic screening using CRISPR–Cas9 is a useful approach to uncover
redundant genes and to explore complex gene networks. However, current methods suffer from …

… well were converted to robust z-scores by z-scoring gene expression relative to corresponding
expression across the entire plate population; these z-scored differential expression gene …

… Scatterplots of Z scores showing knockouts (KOs) that are enriched or depleted in each
drug versus DMSO are shown. KOs are scored by DZDrug = (ZDrug À ZDMSO)/O2 (see STAR …

… on their expression Z-score in Ppm1d gRNA IUE DMG (n = 3 tumors). Top genes with
expression Z-score > 15 are depicted. B Venn diagram showing highly expressed genes (Z-score …

Epigenetic dysregulation is at the core of H3K27M-glioma tumorigenesis. Here, we identify
the BRG1–BAF complex as a critical regulator of enhancer and transcription factor …

Spheroid culture systems have allowed in vitro propagation of cells unable to grow in
canonical cell culturing conditions, and may capture cellular contexts that model tumor growth …

A ck n ow ledgments: We would like to thank the University of Shahid Sadoghi for their coope
ration in this study. We also thank the nursing and midwife ry staff of the Shahid Sadooghi …

Sensory stimulation in patients with a decreased level of consciousness in the intensive
care unit (ICU) can affect the level of consciousness. Thus, this study was conducted to …

… Wherein N is the desired sample size, \({Z}_{\alpha }\) is the standard normal score of 95%
of confidence interval = 1.96, \({Z}_{\beta }\)= statistical power at 80%, which is 0.84 and \(c=0\)…