We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC).
Using this dataset, we expand the catalogue of known ACC driver genes to include …

Squamous cell carcinomas (SCCs) are one of the most frequent forms of human malignancy,
but, other than TP53 mutations, few causative somatic aberrations have been identified. …

Background First-generation molecular profiles for human breast cancers have enabled the
identification of features that can predict therapeutic response; however, little is known about …

Glioma diagnosis is based on histomorphology and grading; however, such classification
does not have predictive clinical outcome after glioblastomas have developed. To date, no …

We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

… Zachary Sanborn … where Z is the normalization constant introduced in Equation (1). Similarly,
the probability that x i is in state a along with all of the observations made for the patient is: …

In recent years, there has been increased interest in carcinomas of the urologic tract, that
demonstrate association with the polyoma virus BK arising in immunosuppressed individuals, …

Desmoplastic melanoma is an uncommon variant of melanoma with sarcomatous histology,
distinct clinical behavior and unknown pathogenesis 1 , 2 , 3 . We performed low-coverage …

To the Editor: Advances in high-throughput genomics have reshaped the cancer research
landscape. Complete characterization of genomic, epigenomic and transcriptomic changes of …

Melanoma is difficult to treat once it becomes metastatic. However, the precise ancestral
relationship between primary tumors and their metastases is not well understood. We performed …