[HTML][HTML] Generation and evaluation of synthetic patient data

…, P Ray, B Soper, J Stevens, L Coyle, AP Sales - BMC medical research …, 2020 - Springer
Background Machine learning (ML) has made a significant impact in medicine and cancer
research; however, its impact in these areas has been undeniably slower and more limited …

[HTML][HTML] Tissue-specific extracellular matrix accelerates the formation of neural networks and communities in a neuron-glia co-culture on a multi-electrode array

D Lam, HA Enright, J Cadena, SKG Peters, AP Sales… - Scientific reports, 2019 - nature.com
The brain’s extracellular matrix (ECM) is a macromolecular network composed of
glycosaminoglycans, proteoglycans, glycoproteins, and fibrous proteins. In vitro studies often use …

[HTML][HTML] A flexible 3-dimensional microelectrode array for in vitro brain models

…, M Triplett, P Karande, SKG Peters, AP Sales… - Lab on a Chip, 2020 - pubs.rsc.org
Three-dimensional (3D) in vitro models have become increasingly popular as systems to
study cell–cell and cell–ECM interactions dependent on the spatial, mechanical, and chemical …

[HTML][HTML] Functional and transcriptional characterization of complex neuronal co-cultures

HA Enright, D Lam, A Sebastian, AP Sales, J Cadena… - Scientific reports, 2020 - nature.com
Brain-on-a-chip systems are designed to simulate brain activity using traditional in vitro cell
culture on an engineered platform. It is a noninvasive tool to screen new drugs, evaluate …

[HTML][HTML] Evaluation of in vitro neuronal platforms as surrogates for in vivo whole brain systems

AM Belle, HA Enright, AP Sales, K Kulp, J Osburn… - Scientific reports, 2018 - nature.com
… Ana Paula SalesA p value of <0.05 was considered significant. All error bars indicate
standard error of the mean (SEM). … Belle, Ana Paula Sales & Elizabeth K. Wheeler …

[HTML][HTML] Flexible, cluster-based analysis of the electronic medical record of sepsis with composite mixture models

MB Mayhew, BK Petersen, AP Sales, JD Greene… - Journal of biomedical …, 2018 - Elsevier
The widespread adoption of electronic medical records (EMRs) in healthcare has provided
vast new amounts of data for statistical machine learning researchers in their efforts to model …

Diversity in smallholder dairy production systems in the Brazilian semiarid region: farm typologies and characteristics of raw milk and water used in milking

…, WHO Vega, DC Sales, AP Sales… - Journal of Arid …, 2022 - Elsevier
… e p ⋮ X p = a p 1 × F 1 + a p 1 × F 2 + ⋯ + a p m × F m + e p where X p is the pth score of the
standardized variable (p = 1, 2, …, m), F m is the extracted factor, a p m is the factor loading, …

[HTML][HTML] Histopathological and immunological characteristics of placentas infected with chikungunya virus

…, TM De Souza, P Nunes, M Lima, AP Sales… - Frontiers in …, 2022 - frontiersin.org
Although vertical transmission of CHIKV has been reported, little is known about the role of
placenta in the transmission of this virus and the effects of infection on the maternal-fetal …

Machine learning applied to understand perceptions, habits and preferences of lamb meat consumers in the Brazilian semi-arid region

…, A Paveloski, LB De Vecchi, AP Sales… - Small Ruminant …, 2023 - Elsevier
The objective of this study was to characterize the profile of the lamb consumer in the Brazilian
semi-arid region using a machine learning approach. A total of 347 questionnaires with …

[HTML][HTML] Zika virus infects human placental mast cells and the HMC-1 cell line, and triggers degranulation, cytokine release and ultrastructural changes

K Rabelo, AJS Gonçalves, LJ Souza, AP Sales… - Cells, 2020 - mdpi.com
Zika virus (ZIKV) is an emergent arthropod-borne virus whose outbreak in Brazil has brought
major public health problems. Infected individuals have different symptoms, including rash …