Reactive astrocytes are astrocytes undergoing morphological, molecular, and functional
remodeling in response to injury, disease, or infection of the CNS. Although this remodeling was …

The DNA damage response is a hierarchical process. DNA damage is detected by sensor
proteins such as the MRN complex that transmit the information to transducer proteins such as …

Blistering skin diseases are a group of autoimmune disorders that are characterized by
autoantibodies against structural proteins of the epidermis or the dermal–epidermal junction and …

MicroRNAs are noncoding RNAs of ∼22 nucleotides that suppress translation of target
genes by binding to their mRNA and thus have a central role in gene regulation in health and …

MicroRNAs (MIRs) are a novel group of conserved short ∼22 nucleotide-long RNAs with
important roles in regulating gene expression. We have established a MIR-specific …

Melanoma originates in the epidermis and becomes metastatic after invasion into the dermis.
Prior interactions between melanoma cells and dermis are poorly studied. Here, we show …

Honey has been described in ancient and modern medicine as being effective in the healing
of various infected wounds. In this report we present our experience in nine infants with …

Ataxia-telangiectasia (AT) is a genetic disorder caused by mutational inactivation of the
ATM gene. AT patients display a pleiotropic phenotype and suffer primarily from progressive …

We present a very efficient rigid “unbound” soft docking methodology, which is based on
detection of geometric shape complementarity, allowing liberal steric clash at the interface. The …

Timely negative regulation of the immune system is critical to allow it to perform its duty while
maintaining it under tight control to avoid overactivation. We previously reported that the …