In 2002, world leaders committed, through the Convention on Biological Diversity, to achieve
a significant reduction in the rate of biodiversity loss by 2010. We compiled 31 indicators to …

Using data for 25,780 species categorized on the International Union for Conservation of
Nature Red List, we present an assessment of the status of the world’s vertebrates. One-fifth of …

In 2010, the international community, under the auspices of the Convention on Biological
Diversity, agreed on 20 biodiversity-related “Aichi Targets” to be achieved within a decade. We …

Background Emerging studies indicate that some coronavirus disease 2019 (COVID-19)
patients suffer from persistent symptoms, including breathlessness and chronic fatigue; however…

The recent revolution in tissue-resident macrophage biology has resulted largely from
murine studies performed in C57BL/6 mice. Here, using both C57BL/6 and BALB/c mice, we …

The target adopted by world leaders of significantly reducing the rate of biodiversity loss by
2010 was not met but this stimulated a new suite of biodiversity targets for 2020 adopted by …

Inflammatory bowel disease (IBD) pathogenesis is associated with dysregulated CD4 + Th
cell responses, with intestinal homeostasis depending on the balance between IL-17–…

Nippostrongylus brasiliensis is a well-defined model of type-2 immunity but the early lung-migrating
phase is dominated by innate IL-17A production. In this study, we confirm previous …

Background and Purpose— A major process contributing to cell death in the ischemic brain
is inflammation. Inflammasomes are multimolecular protein complexes that drive …

Biodiversity indicators are widely used tools to help determine rates of biodiversity change
and the success or failure of efforts to conserve it. However, their sufficiency and suitability in …