Ca 2+ regulation of contraction in vertebrate striated muscle is exerted primarily through
effects on the thin filament, which regulate strong cross-bridge binding to actin. Structural and …

Importance Cerebral palsy describes the most common physical disability in childhood and
occurs in 1 in 500 live births. Historically, the diagnosis has been made between age 12 and …

Species distribution models ( SDM s) are used to inform a range of ecological, biogeographical
and conservation applications. However, users often underestimate the strong links …

PURPOSE: To compare the efficacy and safety of pegylated liposomal doxorubicin (PLD) and
topotecan in patients with epithelial ovarian carcinoma that recurred after or didn’t respond …

Purpose Ovarian cancer (OC) patients experiencing progressive disease (PD) within 6
months of platinum-based therapy in the primary setting are considered platinum resistant (Pt-R). …

PURPOSE: Stealth liposomal doxorubicin (Alzal Corp, Palo Alto, CA) has a slower clearance
rate than free doxorubicin, resulting in sustained serum levels. Liposomal encapsulation …

This article presents an economic model that determines the optimal amount to invest to
protect a given set of information. The model takes into account the vulnerability of the …

OBJECTIVE: Provide long-term follow-up data for women treated in a randomized multicenter
study of pegylated liposomal doxorubicin compared with topotecan. METHODS: Patients …

We establish the existence of the top quark using a 67 pb− 1 data sample of pp collisions at
s= 1.8 TeV collected with the Collider Detector at Fermilab (CDF). Employing techniques …

Eukaryotic cells make many types of primary and processed RNAs that are found either in
specific subcellular compartments or throughout the cells. A complete catalogue of these …