Background Antimicrobial resistance (AMR) poses a major threat to human health around
the world. Previous publications have estimated the effect of AMR on incidence, deaths, …

Klebsiella pneumoniae is now recognized as an urgent threat to human health because of
the emergence of multidrug-resistant strains associated with hospital outbreaks and …

Klebsiella pneumoniae is a growing cause of healthcare-associated infections for which
multi-drug resistance is a concern. Its polysaccharide capsule is a major virulence determinant …

Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections,
which are increasingly complicated by the presence of extended-spectrum beta-lactamases (…

Mobile genetic elements (MGEs) that frequently transfer within and between bacterial
species play a critical role in bacterial evolution, and often carry key accessory genes that …

Klebsiella pneumoniae has emerged as an important cause of two distinct public health
threats: multi-drug resistant (MDR) healthcare-associated infections and drug susceptible …

There is growing evidence of the efficacy of treating early staphylococcal infections of prosthetic
joints with surgical debridement and prosthesis retention, combined with oral antibiotic …

Despite the success of PD-1 blockade in melanoma and other cancers, effective treatment
strategies to overcome resistance to cancer immunotherapy are lacking 1 , 2 . Here we …

From a prospective melioidosis study commencing in 1989 at Royal Darwin Hospital, 170
initial isolates of Burkholderia pseudomallei were available for susceptibility testing. Of these …

Background. Klebsiella pneumoniae is an opportunistic pathogen and leading cause of
hospital-associated infections. Intensive care unit (ICU) patients are particularly at risk. …