User profiles for A. Leemans
Alexander LeemansAssociate Professor, UMC Utrecht, The Netherlands Verified email at umcutrecht.nl Cited by 25808 |
[HTML][HTML] Diffusion tensor imaging and beyond
The diffusion of water molecules inside organic tissues is often anisotropic (1). Namely, if
there are aligned structures in the tissue, the apparent diffusion coefficient (ADC) of water may …
there are aligned structures in the tissue, the apparent diffusion coefficient (ADC) of water may …
Diffusion MRI fiber tractography of the brain
The ability of fiber tractography to delineate non‐invasively the white matter fiber pathways
of the brain raises possibilities for clinical applications and offers enormous potential for …
of the brain raises possibilities for clinical applications and offers enormous potential for …
[HTML][HTML] The challenge of mapping the human connectome based on diffusion tractography
Tractography based on non-invasive diffusion imaging is central to the study of human brain
connectivity. To date, the approach has not been systematically validated in ground truth …
connectivity. To date, the approach has not been systematically validated in ground truth …
Microstructural maturation of the human brain from childhood to adulthood
Brain maturation is a complex process that continues well beyond infancy, and adolescence
is thought to be a key period of brain rewiring. To assess structural brain maturation from …
is thought to be a key period of brain rewiring. To assess structural brain maturation from …
The B‐matrix must be rotated when correcting for subject motion in DTI data
To estimate diffusion tensor MRI (DTI) measures, such as fractional anisotropy and fiber
orientation, reliably, a large number of diffusion‐encoded images is needed, preferably cardiac …
orientation, reliably, a large number of diffusion‐encoded images is needed, preferably cardiac …
Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging
It has long been recognized that the diffusion tensor model is inappropriate to characterize
complex fiber architecture, causing tensor‐derived measures such as the primary eigenvector …
complex fiber architecture, causing tensor‐derived measures such as the primary eigenvector …
Weighted linear least squares estimation of diffusion MRI parameters: strengths, limitations, and pitfalls
Purpose Linear least squares estimators are widely used in diffusion MRI for the estimation
of diffusion parameters. Although adding proper weights is necessary to increase the …
of diffusion parameters. Although adding proper weights is necessary to increase the …
Methodological considerations on tract-based spatial statistics (TBSS)
Having gained a tremendous amount of popularity since its introduction in 2006, tract-based
spatial statistics (TBSS) can now be considered as the standard approach for voxel-based …
spatial statistics (TBSS) can now be considered as the standard approach for voxel-based …
[PDF][PDF] Longitudinal assessment of chemotherapy-induced structural changes in cerebral white matter and its correlation with impaired cognitive functioning
Purpose To uncover the neural substrate of cognitive impairment related to adjuvant
chemotherapy, we studied cerebral white matter (WM) integrity before and after chemotherapy by …
chemotherapy, we studied cerebral white matter (WM) integrity before and after chemotherapy by …
Probabilistic fiber tracking using the residual bootstrap with constrained spherical deconvolution
Constrained spherical deconvolution (CSD) is a new technique that, based on high‐angular
resolution diffusion imaging (HARDI) MR data, estimates the orientation of multiple …
resolution diffusion imaging (HARDI) MR data, estimates the orientation of multiple …