… Among those genes, one could mention CD179b, for progenitor B cells to precursor B cells
differentiation; dntt, required for the V-DJ recombination; or CD4 and CD8a, for thymocytes …

… (B) The subsequent adaptation step is described by the crystal structure of the 70S
initiation … The transition from A to B demands unfolding of the mRNA structures involving the …

… The A/B region is the most divergent among the nuclear receptors and contains an … (a
and b) Comparison of the β sheet region of RARγ (a) and VDR (b) in the same orientation. The …

… all B factors to 0 and calculated two maps at 3.8 and 7.4 Å resolution. We then sampled B
factors in the range 0–500 Å 2 and applied each trial B factor as an overall blurring B factor to …

… 50) was applied to the final maps for appropriate masking, B-factor sharpening and
resolution validation to avoid over-fitting 51 . In this procedure, the appropriate B-factor was …

… (b) Simplified scheme of the initiation of eukaryotic protein synthesis. The 40S subunit
enters the pathway after dissociation from 60S with the help of eIF6, then eIF1A, eIF3, and eIF1 …

… b, A representative region illustrating the quality of the map and the high-resolution
structural features; see also Extended Data Fig. 3. The map visualizes protein methylations and …

… b, Methylation activity of recombinant wild-type ZCCHC4 or catalytically dead mutant on
RNA probes containing distinct sequence motifs (GGACU, GAACU and AAACU, indicated in …

… b, Two pairs of representative class averages and the … b, IF2 positions before and after
joining of the ribosomal subunits 13 … a and b to adopt their positions in 70S initiation complexes. …

Transcription regulation by steroid hormones and other metabolites is mediated by nuclear
receptors (NRs) such as the vitamin D and retinoid X receptors (VDR and RXR). Here, we …