User profiles for B. Mensh

Brett Mensh

Scientific Advisor, Howard Hughes Medical Institute, Janelia Research Campus
Verified email at janelia.hhmi.org
Cited by 6165

[HTML][HTML] A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale

…, R Kötter, HA Lester, JM Lin, BD Mensh… - PLoS computational …, 2009 - journals.plos.org
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains
surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into …

Bright and photostable chemigenetic indicators for extended in vivo voltage imaging

…, J Zheng, JB Grimm, R Patel, J Friedrich, BD Mensh… - Science, 2019 - science.org
Genetically encoded voltage indicators (GEVIs) enable monitoring of neuronal activity at high
spatial and temporal resolution. However, the utility of existing GEVIs has been limited by …

A multilevel multimodal circuit enhances action selection in Drosophila

…, JV Aleman, R Franconville, M Rivera-Alba, BD Mensh… - Nature, 2015 - nature.com
b, Chordotonal and MD IV neurons from each hemisegment project to distinct modality-specific
ventrolateral and ventromedial regions of the nerve cord, respectively. A, anterior; P, …

[PDF][PDF] Dopamine is required for the neural representation and control of movement vigor

…, Y Li, AR Graves, A Vollmer, L Olson, BD Mensh… - Cell, 2015 - cell.com
… MitoPark behavior was characterized by sustained non-zero b values that extended for
several trials of reward history. Thus, our data suggest that dopamine depletion does not impair …

Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells

…, K Sugino, Y Shima, C Guo, S Bai, BD Mensh… - Elife, 2013 - elifesciences.org
10.7554/eLife.00400.001 Cerebellar granule cells constitute the majority of neurons in the
brain and are the primary conveyors of sensory and motor-related mossy fiber information to …

[PDF][PDF] Glia accumulate evidence that actions are futile and suppress unsuccessful behavior

…, S Narayan, CT Yang, M Tanimoto, BD Mensh… - Cell, 2019 - cell.com
When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …

Cortical pattern generation during dexterous movement is input-driven

…, M Mischiati, W Guo, M Kabra, N Verma, B Mensh… - Nature, 2020 - nature.com
b, Neural population activity aligned to the end of the laser for trials with (blue) and without
(red… Suppose we have two types of trial, A and B. In Fig. 2e, these types correspond to trials in …

Thalamus provides layer 4 of primary visual cortex with orientation-and direction-tuned inputs

W Sun, Z Tan, BD Mensh, N Ji - Nature neuroscience, 2016 - nature.com
… (b,c) Calcium transients ΔF/F (b) and tuning curves (c) of the somata in a. Light gray
background in b indicates 6-s drifting grating (topmost labels) presentation. Dark gray shade in b

[PDF][PDF] Hippocampal pyramidal neurons comprise two distinct cell types that are countermodulated by metabotropic receptors

AR Graves, SJ Moore, EB Bloss, BD Mensh, WL Kath… - Neuron, 2012 - cell.com
Relating the function of neuronal cell types to information processing and behavior is a
central goal of neuroscience. In the hippocampus, pyramidal cells in CA1 and the subiculum …

A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons

KD Micheva, D Wolman, BD Mensh, E Pax… - elife, 2016 - elifesciences.org
… Red and green rectangles indicate areas of detail in B and E, respectively. (B) Detail view of
… (C) A reconstructed axon arbor arising from the myelinated tracing seed at the center of B. …