User profiles for B. Mensh
Brett MenshScientific Advisor, Howard Hughes Medical Institute, Janelia Research Campus Verified email at janelia.hhmi.org Cited by 6165 |
[HTML][HTML] A proposal for a coordinated effort for the determination of brainwide neuroanatomical connectivity in model organisms at a mesoscopic scale
In this era of complete genomes, our knowledge of neuroanatomical circuitry remains
surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into …
surprisingly sparse. Such knowledge is critical, however, for both basic and clinical research into …
Bright and photostable chemigenetic indicators for extended in vivo voltage imaging
Genetically encoded voltage indicators (GEVIs) enable monitoring of neuronal activity at high
spatial and temporal resolution. However, the utility of existing GEVIs has been limited by …
spatial and temporal resolution. However, the utility of existing GEVIs has been limited by …
A multilevel multimodal circuit enhances action selection in Drosophila
… b, Chordotonal and MD IV neurons from each hemisegment project to distinct modality-specific
ventrolateral and ventromedial regions of the nerve cord, respectively. A, anterior; P, …
ventrolateral and ventromedial regions of the nerve cord, respectively. A, anterior; P, …
[PDF][PDF] Dopamine is required for the neural representation and control of movement vigor
… MitoPark behavior was characterized by sustained non-zero b values that extended for
several trials of reward history. Thus, our data suggest that dopamine depletion does not impair …
several trials of reward history. Thus, our data suggest that dopamine depletion does not impair …
Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells
10.7554/eLife.00400.001 Cerebellar granule cells constitute the majority of neurons in the
brain and are the primary conveyors of sensory and motor-related mossy fiber information to …
brain and are the primary conveyors of sensory and motor-related mossy fiber information to …
[PDF][PDF] Glia accumulate evidence that actions are futile and suppress unsuccessful behavior
When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …
passive, which can be strategic for preserving energy or regrouping between attempts. It is …
Cortical pattern generation during dexterous movement is input-driven
… b, Neural population activity aligned to the end of the laser for trials with (blue) and without
(red… Suppose we have two types of trial, A and B. In Fig. 2e, these types correspond to trials in …
(red… Suppose we have two types of trial, A and B. In Fig. 2e, these types correspond to trials in …
Thalamus provides layer 4 of primary visual cortex with orientation-and direction-tuned inputs
… (b,c) Calcium transients ΔF/F (b) and tuning curves (c) of the somata in a. Light gray
background in b indicates 6-s drifting grating (topmost labels) presentation. Dark gray shade in b …
background in b indicates 6-s drifting grating (topmost labels) presentation. Dark gray shade in b …
[PDF][PDF] Hippocampal pyramidal neurons comprise two distinct cell types that are countermodulated by metabotropic receptors
Relating the function of neuronal cell types to information processing and behavior is a
central goal of neuroscience. In the hippocampus, pyramidal cells in CA1 and the subiculum …
central goal of neuroscience. In the hippocampus, pyramidal cells in CA1 and the subiculum …
A large fraction of neocortical myelin ensheathes axons of local inhibitory neurons
KD Micheva, D Wolman, BD Mensh, E Pax… - elife, 2016 - elifesciences.org
… Red and green rectangles indicate areas of detail in B and E, respectively. (B) Detail view of
… (C) A reconstructed axon arbor arising from the myelinated tracing seed at the center of B. …
… (C) A reconstructed axon arbor arising from the myelinated tracing seed at the center of B. …