User profiles for C. B. Cole

Christopher B Cole

Deep Genomics
Verified email at deepgenomics.com
Cited by 503

A package of sexual and reproductive health and rights interventions—what does it mean for adolescents?

…, DA Ross, V Chandra-Mouli, CB Cole… - Journal of Adolescent …, 2019 - Elsevier
This article analyzes the relevance of the comprehensive definition of sexual and reproductive
health and rights (SRHR) to adolescents and identifies adolescent-specific implications …

Factors influencing the presence of faecal lactobacilli in early infancy.

MA Hall, CB Cole, SL Smith, R Fuller… - Archives of disease in …, 1990 - adc.bmj.com
The faecal flora of 46 preterm infants and 52 born at full term was studied at 10 days of age;
46 born at full term and 37 preterm infants were also studied at 30 days. Viable counts of …

Forward, together: a collaborative path to comprehensive adolescent sexual and reproductive health and rights in our time

M Plesons, CB Cole, G Hainsworth, R Avila… - Journal of Adolescent …, 2019 - Elsevier
The 1994 International Conference on Population and Development established a basis for
the advancement of adolescent sexual and reproductive health and rights (ASRHR) that …

[HTML][HTML] Driving immune responses in the ovarian tumor microenvironment

F Ning, CB Cole, CM Annunziata - Frontiers in Oncology, 2021 - frontiersin.org
Ovarian cancer is the leading cause of death among gynecological neoplasms, with an
estimated 14,000 deaths in 2019. First-line treatment options center around a taxane and …

A community-maintained standard library of population genetic models

JR Adrion, CB Cole, N Dukler, JG Galloway… - elife, 2020 - elifesciences.org
The explosion in population genomic data demands ever more complex modes of analysis,
and increasingly, these analyses depend on sophisticated simulations. Recent advances in …

[HTML][HTML] Haploinsufficiency for DNA methyltransferase 3A predisposes hematopoietic cells to myeloid malignancies

CB Cole, DA Russler-Germain, S Ketkar… - The Journal of …, 2017 - Am Soc Clin Investig
The gene that encodes de novo DNA methyltransferase 3A (DNMT3A) is frequently mutated
in acute myeloid leukemia genomes. Point mutations at position R882 have been shown to …

[HTML][HTML] Defining the global health system and systematically mapping its network of actors

SJ Hoffman, CB Cole - Globalization and health, 2018 - Springer
Background The global health system has faced significant expansion over the past few
decades, including continued increase in both the number and diversity of actors operating …

LanceOtron: a deep learning peak caller for genome sequencing experiments

LD Hentges, MJ Sergeant, CB Cole, DJ Downes… - …, 2022 - academic.oup.com
Motivation Genome sequencing experiments have revolutionized molecular biology by allowing
researchers to identify important DNA-encoded elements genome wide. Regions where …

[HTML][HTML] First-in-human phase 1 clinical trial of anti-core 1 O-glycans targeting monoclonal antibody NEO-201 in treatment-refractory solid tumors

CB Cole, MP Morelli, M Fantini, M Miettinen… - Journal of Experimental …, 2023 - Springer
Background NEO201 is a humanized IgG1 monoclonal antibody (mAb) generated against
tumor-associated antigens from patients with colorectal cancer. NEO-201 binds to core 1 or …

The influence of the host on expression of intestinal microbial enzyme activities involved in metabolism of foreign compounds

CB Cole, R Fuller, AK Mallet… - Journal of Applied …, 1985 - academic.oup.com
The activities of four enzymes (β‐glucosidase, β‐glucuronidase, nitrate reductase and
nitroreductase) in selected intestinal bacteria (Escherichia coli, Clostridium sp., Streptococcus sp., …