User profiles for C. S. Smukowski Heil
Caiti Smukowski HeilNorth Carolina State University Verified email at ncsu.edu Cited by 857 |
Loss of heterozygosity drives adaptation in hybrid yeast
CS Smukowski Heil, CG DeSevo, DA Pai… - Molecular biology …, 2017 - academic.oup.com
Hybridization is often considered maladaptive, but sometimes hybrids can invade new
ecological niches and adapt to novel or stressful environments better than their parents. The …
ecological niches and adapt to novel or stressful environments better than their parents. The …
Recombining without Hotspots: A Comprehensive Evolutionary Portrait of Recombination in Two Closely Related Species of Drosophila
CS Smukowski Heil, C Ellison, M Dubin… - Genome biology and …, 2015 - academic.oup.com
Meiotic recombination rate varies across the genome within and between individuals,
populations, and species in virtually all taxa studied. In almost every species, this variation takes …
populations, and species in virtually all taxa studied. In almost every species, this variation takes …
[HTML][HTML] Temperature preference can bias parental genome retention during hybrid evolution
Interspecific hybridization can introduce genetic variation that aids in adaptation to new or
changing environments. Here, we investigate how hybrid adaptation to temperature and …
changing environments. Here, we investigate how hybrid adaptation to temperature and …
Selection on heterozygosity drives adaptation in intra-and interspecific hybrids
CS Smukowski Heil, CG DeSevo, DA Pai, CM Tucker… - bioRxiv, 2016 - biorxiv.org
Hybridization is often considered maladaptive, but sometimes hybrids can invade new ecological
niches and adapt to novel or stressful environments better than their parents. However, …
niches and adapt to novel or stressful environments better than their parents. However, …
Experimental evolution reveals favored adaptive routes to cell aggregation in yeast
Yeast flocculation is a community-building cell aggregation trait that is an important mechanism
of stress resistance and a useful phenotype for brewers; however, it is also a nuisance in …
of stress resistance and a useful phenotype for brewers; however, it is also a nuisance in …
Fitness benefits of loss of heterozygosity in Saccharomyces hybrids
With two genomes in the same organism, interspecific hybrids have unique fitness opportunities
and costs. In both plants and yeasts, wild, pathogenic, and domesticated hybrids may …
and costs. In both plants and yeasts, wild, pathogenic, and domesticated hybrids may …
[HTML][HTML] Loss of heterozygosity and its importance in evolution
CS Heil - Journal of molecular evolution, 2023 - ncbi.nlm.nih.gov
… uvarum hemizygous genes underlying two different LOH events in hybrids evolved in low
phosphate (Smukowski Heil et al. 2017). More broadly, these experiments found that beneficial …
phosphate (Smukowski Heil et al. 2017). More broadly, these experiments found that beneficial …
The recombination landscape of introgression in yeast
EJ Schwarzkopf, N Brandt, C Smukowski Heil - bioRxiv, 2024 - biorxiv.org
Meiotic recombination is an evolutionary force that acts by breaking up genomic linkage,
increasing the efficacy of selection. Recombination is initiated with a double-strand break which …
increasing the efficacy of selection. Recombination is initiated with a double-strand break which …
[HTML][HTML] Loss of heterozygosity drives adaptation in hybrid yeast
CSS Heil, CG DeSevo, DA Pai, CM Tucker… - … biology and evolution, 2017 - ncbi.nlm.nih.gov
Hybridization is often considered maladaptive, but sometimes hybrids can invade new
ecological niches and adapt to novel or stressful environments better than their parents. The …
ecological niches and adapt to novel or stressful environments better than their parents. The …
Identification of a novel interspecific hybrid yeast from a metagenomic open fermentation sample using Hi-C
CS Heil, JN Burton, I Liachko, A Friedrich, NA Hanson… - bioRxiv, 2017 - biorxiv.org
Interspecific hybridization is a common mechanism enabling genetic diversification and
adaptation; however, the detection of hybrid species has been quite difficult. The identification of …
adaptation; however, the detection of hybrid species has been quite difficult. The identification of …