User profiles for C. T. Hittinger

Chris Todd Hittinger

Professor of Genetics, University of Wisconsin-Madison
Verified email at wisc.edu
Cited by 9835

Toward a fully resolved fungal tree of life

TY James, JE Stajich, CT Hittinger… - Annual Review of …, 2020 - annualreviews.org
In this review, we discuss the current status and future challenges for fully elucidating the
fungal tree of life. In the last 15 years, advances in genomic technologies have revolutionized …

Saccharomyces diversity and evolution: a budding model genus

CT Hittinger - Trends in Genetics, 2013 - cell.com
Saccharomyces cerevisiae is one of the best-understood and most powerful genetic model
systems. Several disciplines are now converging to turn Saccharomyces into an exciting …

New yeasts—new brews: modern approaches to brewing yeast design and development

B Gibson, JMA Geertman, CT Hittinger… - FEMS Yeast …, 2017 - academic.oup.com
The brewing industry is experiencing a period of change and experimentation largely driven
by customer demand for product diversity. This has coincided with a greater appreciation of …

Microbe domestication and the identification of the wild genetic stock of lager-brewing yeast

D Libkind, CT Hittinger, E Valério… - Proceedings of the …, 2011 - National Acad Sciences
Domestication of plants and animals promoted humanity's transition from nomadic to sedentary
lifestyles, demographic expansion, and the emergence of civilizations. In contrast to the …

Gene duplication and the adaptive evolution of a classic genetic switch

CT Hittinger, SB Carroll - Nature, 2007 - nature.com
How gene duplication and divergence contribute to genetic novelty and adaptation has
been of intense interest, but experimental evidence has been limited. The genetic switch …

Evolution of key cell signaling and adhesion protein families predates animal origins

N King, CT Hittinger, SB Carroll - Science, 2003 - science.org
The evolution of animals from a unicellular ancestor involved many innovations.
Choanoflagellates, unicellular and colonial protozoa closely related to Metazoa, provide a potential …

[PDF][PDF] Tempo and mode of genome evolution in the budding yeast subphylum

…, M Groenewald, CP Kurtzman, CT Hittinger… - Cell, 2018 - cell.com
… We thank members of the Rokas and Hittinger labs, in particular Abigail L. LaBella, for
feedback and discussions on the project; Mario dos Reis, Qiqing Tao, and Sudhir Kumar for …

Contentious relationships in phylogenomic studies can be driven by a handful of genes

XX Shen, CT Hittinger, A Rokas - Nature ecology & evolution, 2017 - nature.com
Phylogenomic studies have resolved countless branches of the tree of life, but remain strongly
contradictory on certain, contentious relationships. Here, we use a maximum likelihood …

The Awesome Power of Yeast Evolutionary Genetics: New Genome Sequences and Strain Resources for the Saccharomyces sensu stricto Genus

…, J Rine, M Johnston, CT Hittinger - G3: Genes …, 2011 - academic.oup.com
High-quality, well-annotated genome sequences and standardized laboratory strains fuel
experimental and evolutionary research. We present improved genome sequences of three …

Identifying genes of agronomic importance in maize by screening microsatellites for evidence of selection during domestication

…, M McMullen, CT Hittinger… - Proceedings of the …, 2002 - National Acad Sciences
Crop species experienced strong selective pressure directed at genes controlling traits of
agronomic importance during their domestication and subsequent episodes of selective …