PURPOSE: In a previous study of treatment for advanced colorectal cancer, the LV5FU2
regimen, comprising leucovorin (LV) plus bolus and infusional fluorouracil (5FU) every 2 weeks, …

A great effort of research has been devoted in the last few years to developing new anti-HBV
therapies of finite duration that also provide effective sustained control of virus replication …

Background The standard adjuvant treatment of colon cancer is fluorouracil plus leucovorin (FL).
Oxaliplatin improves the efficacy of this combination in patients with metastatic …

… 765 mg/m2 (nine cycles) in NSABP C-07, whereas the median oxaliplatin dose received
per … cycles) in NSABP C-07. On the basis of the neurotoxicity data in MOSAIC10 and C-07,19 …

… A vigorous and Th1 oriented HLA class II restricted peripheral blood T cell response to
hepatitis B c antigen (HBcAg) and hepatitis B e antigen (HBeAg) is detectable in virtually all …

… Enveloped virions are essential for spread, and their formation requires viral factors (C
terminus of preS1 domain, N terminus of preS2) and host factors (endosomal sorting complexes …

Purpose: To evaluate whether two commonly used newer platinum-based regimens offer any
advantage over vinorelbine-cisplatin (reference regimen) in response rate for patients with …

Purpose In the randomized, multinational phase II/III trial (V325) of untreated advanced gastric
cancer patients, the phase II part selected docetaxel, cisplatin, and fluorouracil (DCF) over …

… All patients with chronic HBV infection were HBsAg and anti-HBc positive and were negative
for Abs to hepatitis C virus (HCV), delta virus, and to HIV-1 and -2 (except patient 20, who …

Background A fluoropyrimidine plus irinotecan or oxaliplatin, combined with bevacizumab (a
monoclonal antibody against vascular endothelial growth factor), is standard first-line …