User profiles for C. Colantuoni
Carlo ColantuoniDepts. Neurology & Neuroscience, Johns Hopkins SOM & Institute for Genome Sciences, U … Verified email at jhmi.edu Cited by 6485 |
Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence
C Colantuoni, P Rada, J McCarthy, C Patten… - Obesity …, 2002 - Wiley Online Library
Objective: The goal was to determine whether withdrawal from sugar can cause signs of
opioid dependence. Because palatable food stimulates neural systems that are implicated in …
opioid dependence. Because palatable food stimulates neural systems that are implicated in …
Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain
C Colantuoni, J Schwenker, J McCarthy, P Rada… - …, 2001 - journals.lww.com
Palatable food stimulates neural systems implicated in drug dependence; thus sugar might
have effects like a drug of abuse. Rats were given 25% glucose solution with chow for 12 h …
have effects like a drug of abuse. Rats were given 25% glucose solution with chow for 12 h …
Temporal dynamics and genetic control of transcription in the human prefrontal cortex
… c, A global view of dynamic PFC transcription across the lifespan, using MDS (distance = 1
− r, stress = 20.5) and expression correlation. Each mRNA sample is represented as a single …
− r, stress = 20.5) and expression correlation. Each mRNA sample is represented as a single …
[PDF][PDF] DNA methylation signatures in development and aging of the human prefrontal cortex
…, R Tao, M Wininger, C Colantuoni… - The American Journal of …, 2012 - cell.com
The human prefrontal cortex (PFC), a mastermind of the brain, is one of the last brain regions
to mature. To investigate the role of epigenetics in the development of PFC, we examined …
to mature. To investigate the role of epigenetics in the development of PFC, we examined …
Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia
…, OE Metitiri, RE Straub, T Ye, C Colantuoni… - Journal of …, 2011 - Soc Neuroscience
GABA signaling molecules are critical for both human brain development and the
pathophysiology of schizophrenia. We examined the expression of transcripts derived from three …
pathophysiology of schizophrenia. We examined the expression of transcripts derived from three …
Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis
…, HS Xi, J Quan, Q Chen, C Colantuoni… - Nature …, 2018 - nature.com
… c,d, Association (c) between rs3849046 and a splice junction of a particular long isoform (d)
of CNNTA1. e,f, Association (e) between rs9841616 and very proximal extended UTR (f) of …
of CNNTA1. e,f, Association (e) between rs9841616 and very proximal extended UTR (f) of …
[HTML][HTML] A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain 1 , 2 – 3 . With the proliferation of multi-omics …
samples of the diverse cell types in the brain 1 , 2 – 3 . With the proliferation of multi-omics …
Convergence of placenta biology and genetic risk for schizophrenia
…, KF Berman, MF Egan, RE Straub, C Colantuoni… - Nature medicine, 2018 - nature.com
Defining the environmental context in which genes enhance disease susceptibility can
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …
High throughput analysis of gene expression in the human brain
C Colantuoni, AE Purcell, CML Bouton… - Journal of …, 2000 - Wiley Online Library
… brain dead for 8 days prior to clinical death (Colantuoni et al., unpublished). Other factors
that … By using the technique of subtractive hybridization (see below), we identified hepatitis C …
that … By using the technique of subtractive hybridization (see below), we identified hepatitis C …
gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration
To the Editor—Biologists are important stakeholders in genomic data, both as data generators
and as users of genomic data resources. Tools to efficiently visualize and analyze multi-…
and as users of genomic data resources. Tools to efficiently visualize and analyze multi-…