User profiles for C. Colantuoni

Carlo Colantuoni

Depts. Neurology & Neuroscience, Johns Hopkins SOM & Institute for Genome Sciences, U …
Verified email at jhmi.edu
Cited by 6485

Evidence that intermittent, excessive sugar intake causes endogenous opioid dependence

C Colantuoni, P Rada, J McCarthy, C Patten… - Obesity …, 2002 - Wiley Online Library
Objective: The goal was to determine whether withdrawal from sugar can cause signs of
opioid dependence. Because palatable food stimulates neural systems that are implicated in …

Excessive sugar intake alters binding to dopamine and mu-opioid receptors in the brain

C Colantuoni, J Schwenker, J McCarthy, P Rada… - …, 2001 - journals.lww.com
Palatable food stimulates neural systems implicated in drug dependence; thus sugar might
have effects like a drug of abuse. Rats were given 25% glucose solution with chow for 12 h …

Temporal dynamics and genetic control of transcription in the human prefrontal cortex

C Colantuoni, BK Lipska, T Ye, TM Hyde, R Tao… - Nature, 2011 - nature.com
c, A global view of dynamic PFC transcription across the lifespan, using MDS (distance = 1
− r, stress = 20.5) and expression correlation. Each mRNA sample is represented as a single …

[PDF][PDF] DNA methylation signatures in development and aging of the human prefrontal cortex

…, R Tao, M Wininger, C Colantuoni… - The American Journal of …, 2012 - cell.com
The human prefrontal cortex (PFC), a mastermind of the brain, is one of the last brain regions
to mature. To investigate the role of epigenetics in the development of PFC, we examined …

Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia

…, OE Metitiri, RE Straub, T Ye, C Colantuoni… - Journal of …, 2011 - Soc Neuroscience
GABA signaling molecules are critical for both human brain development and the
pathophysiology of schizophrenia. We examined the expression of transcripts derived from three …

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

…, HS Xi, J Quan, Q Chen, C Colantuoni… - Nature …, 2018 - nature.com
c,d, Association (c) between rs3849046 and a splice junction of a particular long isoform (d)
of CNNTA1. e,f, Association (e) between rs9841616 and very proximal extended UTR (f) of …

[HTML][HTML] A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

…, AS Booeshaghi, HC Bravo, T Casper, C Colantuoni… - Nature, 2021 - nature.com
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain 1 , 2 – 3 . With the proliferation of multi-omics …

Convergence of placenta biology and genetic risk for schizophrenia

…, KF Berman, MF Egan, RE Straub, C Colantuoni… - Nature medicine, 2018 - nature.com
Defining the environmental context in which genes enhance disease susceptibility can
provide insight into the pathogenesis of complex disorders. We report that the intra-uterine …

High throughput analysis of gene expression in the human brain

C Colantuoni, AE Purcell, CML Bouton… - Journal of …, 2000 - Wiley Online Library
… brain dead for 8 days prior to clinical death (Colantuoni et al., unpublished). Other factors
that … By using the technique of subtractive hybridization (see below), we identified hepatitis C

gEAR: Gene Expression Analysis Resource portal for community-driven, multi-omic data exploration

…, B Milon, MS Matern, H Azaiez, B Herb, C Colantuoni… - Nature …, 2021 - nature.com
To the Editor—Biologists are important stakeholders in genomic data, both as data generators
and as users of genomic data resources. Tools to efficiently visualize and analyze multi-…