User profiles for C. Houldcroft
Charlotte J. HouldcroftDepartment of Genetics, University of Cambridge Verified email at cam.ac.uk Cited by 4933 |
[HTML][HTML] Clinical and biological insights from viral genome sequencing
Whole-genome sequencing (WGS) of pathogens is becoming increasingly important not only
for basic research but also for clinical science and practice. In virology, WGS is important …
for basic research but also for clinical science and practice. In virology, WGS is important …
[PDF][PDF] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity
…, G Betancor, HD Wilson, T Feltwell, CJ Houldcroft… - Cell, 2021 - cell.com
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …
are suggestive of a selective advantage but may also be due to a random founder effect. We …
Host genetics of Epstein–Barr virus infection, latency and disease
CJ Houldcroft, P Kellam - Reviews in medical virology, 2015 - Wiley Online Library
… In this study of approximately 500 cases and 400 controls, the C allele of SNP rs3813946
was associated with sporadic (non-familial) NPC (OR = 1.43) 86. Following up a number of …
was associated with sporadic (non-familial) NPC (OR = 1.43) 86. Following up a number of …
[HTML][HTML] Rapid implementation of SARS-CoV-2 sequencing to investigate cases of health-care associated COVID-19: a prospective genomic surveillance study
…, WL Hamilton, B Warne, CJ Houldcroft… - The Lancet infectious …, 2020 - thelancet.com
Background The burden and influence of health-care associated severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
syndrome coronavirus 2 (SARS-CoV-2) infections is unknown. We aimed to examine the use …
Severe Epstein–Barr virus infection in primary immunodeficiency and the normal host
…, CJ Houldcroft, C Booth - British journal of …, 2016 - Wiley Online Library
… Charlotte Houldcroft; Writing and research selected sections of the manuscript. Claire
Booth; Writing and research selected sections of the manuscript. Editing of manuscript. …
Booth; Writing and research selected sections of the manuscript. Editing of manuscript. …
Patterns of within-host genetic diversity in SARS-CoV-2
… high C>U error rate in both strands, we would expect a symmetric number of C>U and G>A
mutations in the plus strand, as C… , the dominance of C>U over G>A and G>U over C>A, when …
mutations in the plus strand, as C… , the dominance of C>U over G>A and G>U over C>A, when …
[HTML][HTML] New vegetation albedo parameters and global fields of soil background albedo derived from MODIS for use in a climate model
CJ Houldcroft, WMF Grey, M Barnsley… - Journal of …, 2009 - journals.ametsoc.org
New values are derived for snow-free albedo of five plant functional types (PFTs) and the
soil/litter substrate from data acquired by the Moderate Resolution Imaging Spectroradiometer (…
soil/litter substrate from data acquired by the Moderate Resolution Imaging Spectroradiometer (…
Human cytomegalovirus haplotype reconstruction reveals high diversity due to superinfection and evidence of within-host recombination
J Cudini, S Roy, CJ Houldcroft… - Proceedings of the …, 2019 - National Acad Sciences
… is no greater than that of other DNA viruses analyzed by the same sequencing and
bioinformatic methods and considerably less than that of human immunodeficiency and hepatitis C …
bioinformatic methods and considerably less than that of human immunodeficiency and hepatitis C …
[HTML][HTML] Disease-associated XMRV sequences are consistent with laboratory contamination
… Cycling conditions were 95C for 15 secs and annealing/extension at 60C for 1 minute after
an initial denaturation of 10 min. Thresholds were routinely set at default values. Primers are …
an initial denaturation of 10 min. Thresholds were routinely set at default values. Primers are …
Sampling bias and incorrect rooting make phylogenetic network tracing of SARS-COV-2 infections unreliable
…, SV Scarpino, C Houldcroft… - Proceedings of the …, 2020 - National Acad Sciences
… The central claim is the identification of three main SARS-CoV-2 types, named A, B, and
C, circulating in different proportions among Europeans and Americans (types A and C) and …
C, circulating in different proportions among Europeans and Americans (types A and C) and …