Multiple ancient genome duplications in Arabidopsis thaliana provide unique opportunities
to assess factors that influence the fates of duplicated genes. We have found that genes …

… Trees drawn from protein sequences show that C. albicans … Recent analysis of the available
C. albicans genome … number of contiguous genes (C Seoighe, KH Wolfe, unpublished data). …

The precise identification of the HIV-1 envelope glycoprotein (Env) responsible for
productive clinical infection could be instrumental in elucidating the molecular basis of HIV-1 …

… Moreover, performing NMF on large scale data requires intensive computations; the
ability of R to call external complied code (C/C++, Fortran) allows the integration of optimized …

Probabilistic models of sequence evolution are in widespread use in phylogenetics and
molecular sequence evolution. These models have become increasingly sophisticated and …

… In the present study, we investigated the genetic characteristics of subtype C variants … B
and C viruses. Our results indicate that similar proportions of subtype B and subtype C infections …

Admixed populations present unique opportunities to discover the genetic factors underlying
many multifactorial diseases. The geographical position and complex history of South …

Gene expression data are typically generated from heterogeneous biological samples that
are composed of multiple cell or tissue types, in varying proportions, each contributing to …

The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection
in humans and highlights the importance of understanding protective immunity against HIV…

… Finally, we analysed the HIV-1 subtype C env and gag data of our recent study (Scheffler
and Seoighe manuscript submitted). These datasets contain 10 taxa each, with accession …