Background Both naturalistic studies and treatment research on bipolar disorder are reviewed
to describe its clinical course, the need for maintenance therapy, the efficacy of current …

Significant pleural effusions are infrequently noted in patients with cirrhosis of the liver. A large
effusion (hepatic hydrothorax) occasionally appears during the course of the disease. The …

This article reviews the histologic and molecular characterization of gliomas, including the
new “integrated diagnoses” of the World Health Organization Classification, 2016 edition. The …

Background To our knowledge, this is the first prospective natural history study of weekly
symptomatic status of patients with bipolar I disorder (BP-I) during long-term follow-up. Methods …

Background This is the first prospective longitudinal study, to our knowledge, of the natural
history of the weekly symptomatic status of bipolar II disorder (BP-II). Methods Weekly …

OBJECTIVE: The recurrence of an affective disorder in people who initially recover from major
depressive disorder was characterized by using the unique longitudinal prospective follow…

OBJECTIVE: The authors of this study examined multiple recurrences of unipolar major
depressive disorder. METHOD: A total of 318 subjects with unipolar major depressive disorder …

Context Evidence of psychosocial disability in bipolar disorder is based primarily on bipolar
I disorder (BP-I) and does not relate disability to affective symptom severity and polarity or to …

cIMPACT‐NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor
Taxonomy) was established to evaluate and make practical recommendations on recent …

OBJECTIVE: This study investigated the influence of incomplete recovery from first lifetime
major depressive episodes on long-term outcome. METHOD: After their first lifetime major …