User profiles for D. J. MacIntyre
Donald J MacIntyreUniversity of Edinburgh Verified email at ed.ac.uk Cited by 16772 |
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-wide
association study of 41,917 bipolar disorder cases and 371,549 controls of European …
association study of 41,917 bipolar disorder cases and 371,549 controls of European …
Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder
…, WJ Muir, KA McGhee, R Williamson, DJ MacIntyre… - Nature …, 2008 - nature.com
To identify susceptibility loci for bipolar disorder, we tested 1.8 million variants in 4,387 cases
and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 × 10 −…
and 6,209 controls and identified a region of strong association (rs10994336, P = 9.1 × 10 −…
Genome-wide association study identifies 30 loci associated with bipolar disorder
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
Chromosomal abnormalities and mental illness
DJ MacIntyre, DHR Blackwood, DJ Porteous… - Molecular …, 2003 - nature.com
Linkage studies of mental illness have provided suggestive evidence of susceptibility loci over
many broad chromosomal regions. Pinpointing causative gene mutations by conventional …
many broad chromosomal regions. Pinpointing causative gene mutations by conventional …
Whole-genome association study of bipolar disorder
…, J Franklin, WJ Muir, KA McGhee, DJ MacIntyre… - Molecular …, 2008 - nature.com
We performed a genome-wide association scan in 1461 patients with bipolar (BP) 1 disorder,
2008 controls drawn from the Systematic Treatment Enhancement Program for Bipolar …
2008 controls drawn from the Systematic Treatment Enhancement Program for Bipolar …
[HTML][HTML] Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned
Major depressive disorder (MDD) is a common complex disorder with a partly genetic etiology.
We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, …
We conducted a genome-wide association study of the MDD2000+ sample (2431 cases, …
Beyond mobile apps: a survey of technologies for mental well-being
Mental health problems are on the rise globally and strain national health systems worldwide.
Mental disorders are closely associated with fear of stigma, structural barriers such as …
Mental disorders are closely associated with fear of stigma, structural barriers such as …
Cohort Profile: Generation Scotland: Scottish Family Health Study (GS: SFHS). The study, its participants and their potential for genetic research on health and illness
…, SM Kerr, IJ Deary, DJ MacIntyre… - International journal …, 2013 - academic.oup.com
GS:SFHS is a family-based genetic epidemiology study with DNA and socio-demographic
and clinical data from about 24 000 volunteers across Scotland aged 18–98 years, from …
and clinical data from about 24 000 volunteers across Scotland aged 18–98 years, from …
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
…, Y Hu, M Kohli, D Lin, S Lucae, DJ MacIntyre… - Molecular …, 2009 - nature.com
Major depressive disorder (MDD) is a common complex trait with enormous public health
significance. As part of the Genetic Association Information Network initiative of the US …
significance. As part of the Genetic Association Information Network initiative of the US …