Amyloid-β peptide (Aβ) interacts with the vasculature to influence Aβ levels in the brain and
cerebral blood flow, providing a means of amplifying the Aβ-induced cellular stress …

… cortex (Armstrong et al., 1995). Similar studies are currently in progress with Mecp2308/y mice,
but … A new test for aggression in rats without averArmstrong, D., Dunn, JK, Antalffy, B., and …

The cerebellum is essential for fine motor control of movement and posture, and its
dysfunction disrupts balance and impairs control of speech, limb and eye movements. The …

Rett syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the methyl-CpG-binding
protein 2 (MECP2) gene. Previous data have shown that MECP2 RNA is …

Mutations in the X-linked methyl-CpG-binding protein 2 (MECP2), encoding a transcriptional
repressor, cause Rett syndrome and a variety of related neurodevelopmental disorders. …

FKBP12, a cis–trans prolyl isomerase that binds the immunosuppressants FK506 and
rapamycin, is ubiquitouslyexpressed and interacts with proteins in several intracellular signal …

The enzymatic addition or removal of phosphate esters on serine and threonine hydroxyls
alters the activity of many proteins that contribute to the characteristic structure and function of …

Dendritic branching was evaluated in the visual cortex of 8 children with Down's syndrome
and 10 controls, ranging in age from 4 months to 7 years and divided into infantile, late‐…

Background Although pockets of bioinformatics excellence have developed in Africa, generally,
large-scale genomic data analysis has been limited by the availability of expertise and …

The developmental morphology of visual cortical neurons (their numbers, dendritic arborization
and numbers of spines) in 14 fetuses and infants with Down's syndrome were studied …