[HTML][HTML] The genomic signatures of Shigella evolution, adaptation and geographical spread

HC The, DP Thanh, KE Holt, NR Thomson… - Nature Reviews …, 2016 - nature.com
Shigella spp. are some of the key pathogens responsible for the global burden of diarrhoeal
disease. These facultative intracellular bacteria belong to the family Enterobacteriaceae, …

[HTML][HTML] Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

…, JA Crump, E De Pinna, S Nair, EJ Nilles, DP Thanh… - Nature …, 2015 - nature.com
The emergence of multidrug-resistant (MDR) typhoid is a major global health threat affecting
many countries where the disease is endemic. Here whole-genome sequence analysis of …

Intercontinental dissemination of azithromycin-resistant shigellosis through sexual transmission: a cross-sectional study

…, JD Brown, NK Petty, M Gouali, DP Thanh… - The Lancet infectious …, 2015 - thelancet.com
Background Shigellosis is an acute, severe bacterial colitis that, in high-income countries, is
typically associated with travel to high-risk regions (Africa, Asia, and Latin America). Since …

Tracking the establishment of local endemic populations of an emergent enteric pathogen

KE Holt, TV Thieu Nga, DP Thanh… - Proceedings of the …, 2013 - National Acad Sciences
Shigella sonnei is a human-adapted pathogen that is emerging globally as the dominant agent
of bacterial dysentery. To investigate local establishment, we sequenced the genomes of …

[HTML][HTML] The induction and identification of novel Colistin resistance mutations in Acinetobacter baumannii and their implications

…, DW Riordan, T Do Hoang Nhu, DP Thanh… - Scientific reports, 2016 - nature.com
Acinetobacter baumannii is a significant cause of opportunistic hospital acquired infection
and has been identified as an important emerging infection due to its high levels of …

Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

…, LB Martin, F D'Alessio, DP Thanh… - Clinical Infectious …, 2017 - academic.oup.com
Background. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to
develop the first human challenge model of Salmonella enterica serovar Paratyphi A …

New Variant of Multidrug-Resistant Salmonella enterica Serovar Typhimurium Associated with Invasive Disease in Immunocompromised Patients in Vietnam

…, NT Tue, JI Campbell, MA Rabaa, DP Thanh… - MBio, 2018 - Am Soc Microbiol
Nontyphoidal Salmonella (NTS), particularly Salmonella enterica serovar Typhimurium, is
among the leading etiologic agents of bacterial enterocolitis globally and a well-characterized …

[HTML][HTML] Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial

…, CN Thompson, NTV Thieu, DP Thanh… - The Lancet infectious …, 2016 - thelancet.com
Background Because treatment with third-generation cephalosporins is associated with
slow clinical improvement and high relapse burden for enteric fever, whereas the …

[HTML][HTML] Inducible colistin resistance via a disrupted plasmid-borne mcr-1 gene in a 2008 Vietnamese Shigella sonnei isolate

DP Thanh, HT Tuyen, TNT Nguyen… - Journal of …, 2016 - ncbi.nlm.nih.gov
Objectives The objective of this study was to assess the presence of mcr-1 in Shigella sonnei
isolated in Vietnam. Methods WGS data were analysed for the presence of the mcr-1 gene …

Clinical and laboratory-induced colistin-resistance mechanisms in Acinetobacter baumannii

…, NT Do Hoang, NNT Khanh, DP Thanh… - Microbial …, 2019 - microbiologyresearch.org
The increasing incidence and emergence of multi-drug resistant (MDR) Acinetobacter
baumannii has become a major global health concern. Colistin is a historic antimicrobial that has …