[PDF][PDF] Patronin/Shot cortical foci assemble the noncentrosomal microtubule array that specifies the Drosophila anterior-posterior axis

D Nashchekin, AR Fernandes, D St Johnston - Developmental cell, 2016 - cell.com
Noncentrosomal microtubules play an important role in polarizing differentiated cells, but little
is known about how these microtubules are organized. Here we identify the spectraplakin, …

Nuclear actin is associated with a specific subset of hnRNP A/B-type proteins

P Percipalle, A Jonsson, D Nashchekin… - Nucleic acids …, 2002 - academic.oup.com
Pre-mRNP complexes were isolated from rat liver nuclei as 40S hnRNP particles, and actin-binding
proteins were collected by DNase I affinity chromatography. The bound proteins …

[HTML][HTML] The major core protein of messenger ribonucleoprotein particles (p50) promotes initiation of protein biosynthesis in vitro

VM Evdokimova, EA Kovrigina, DV Nashchekin… - Journal of Biological …, 1998 - ASBMB
The major core protein of cytoplasmic messenger ribonucleoprotein particles (p50) has been
shown previously to inhibit protein synthesis in vitro and in vivo. Furthermore, p50 is highly …

Symmetry breaking in the female germline cyst

D Nashchekin, L Busby, M Jakobs, I Squires… - Science, 2021 - science.org
In mammals and flies, only one cell in a multicellular female germline cyst becomes an
oocyte, but how symmetry is broken to select the oocyte is unknown. Here, we show that the …

bicoid mRNA localises to the Drosophila oocyte anterior by random Dynein-mediated transport and anchoring

V Trovisco, K Belaya, D Nashchekin, U Irion… - Elife, 2016 - elifesciences.org
10.7554/eLife.17537.001 bicoid mRNA localises to the Drosophila oocyte anterior from
stage 9 of oogenesis onwards to provide a local source for Bicoid protein for embryonic …

A p50-like Y-box protein with a putative translational role becomes associated with pre-mRNA concomitant with transcription

T Soop, D Nashchekin, J Zhao, X Sun… - Journal of cell …, 2003 - journals.biologists.com
In vertebrates free messenger ribonucleoprotein (RNP) particles and polysomes contain an
abundant Y-box protein called p50 (YB-1), which regulates translation, presumably by …

Anterior–Posterior Axis Specification in Drosophila Oocytes: Identification of Novel bicoid and oskar mRNA Localization Factors

CW Chang, D Nashchekin, L Wheatley, U Irion… - Genetics, 2011 - academic.oup.com
The Drosophila melanogaster anterior–posterior axis is established during oogenesis by
the localization of bicoid and oskar mRNAs to the anterior and posterior poles of the oocyte. …

[HTML][HTML] A novel Ded1-like RNA helicase interacts with the Y-box protein ctYB-1 in nuclear mRNP particles and in polysomes

D Nashchekin, J Zhao, N Visa, B Daneholt - Journal of Biological Chemistry, 2006 - ASBMB
We have characterized a novel mRNA-binding protein, designated hrp84, in the dipteran
Chironomus tentans and identified it as a DEAD-box RNA helicase. The protein contains the …

Localised dynactin protects growing microtubules to deliver oskar mRNA to the posterior cortex of the Drosophila oocyte

R Nieuwburg, D Nashchekin, M Jakobs, AP Carter… - Elife, 2017 - elifesciences.org
… -type egg chamber (D) and an egg chamber … D) Wild-type (C–C’’) and arp14D2 (DD’’)
mutant stage 9 egg chambers stained for p150Glued (C–D) and the dynein heavy chain (C’–D

User-friendly oblique plane microscopy on a fully functional commercially available microscope base

G Sirinakis, ES Allgeyer, D Nashchekin… - Biomedical Optics …, 2024 - opg.optica.org
In this work we present an oblique plane microscope designed to work seamlessly with a
commercially available microscope base. To support all the functionality offered by the …