User profiles for E. E. Burke
Emily E. BurkeNeumora Therapeutics Verified email at neumoratx.com Cited by 835 |
Vaccine therapies for breast cancer
EE Burke, K Kodumudi… - Surgical Oncology …, 2019 - surgonc.theclinics.com
Breast cancer remains the most commonly diagnosed cancer and accounts for the second
leading cause of cancer-related deaths in women in the United States. 1 Given that 1 in 8 …
leading cause of cancer-related deaths in women in the United States. 1 Given that 1 in 8 …
[PDF][PDF] Regional heterogeneity in gene expression, regulation, and coherence in the frontal cortex and hippocampus across development and schizophrenia
L Collado-Torres, EE Burke, A Peterson, JH Shin… - Neuron, 2019 - cell.com
The hippocampus formation, although prominently implicated in schizophrenia pathogenesis,
has been overlooked in large-scale genomics efforts in the schizophrenic brain. We …
has been overlooked in large-scale genomics efforts in the schizophrenic brain. We …
Analysis of the caudate nucleus transcriptome in individuals with schizophrenia highlights effects of antipsychotics and new risk genes
Most studies of gene expression in the brains of individuals with schizophrenia have focused
on cortical regions, but subcortical nuclei such as the striatum are prominently implicated in …
on cortical regions, but subcortical nuclei such as the striatum are prominently implicated in …
Religion as a means to assure paternity
…, NT Kurapati, BF Hug, EE Burke… - Proceedings of the …, 2012 - National Acad Sciences
The sacred texts of five world religions (Buddhism, Christianity, Hinduism, Islam, and Judaism)
use similar belief systems to set limits on sexual behavior. We propose that this similarity …
use similar belief systems to set limits on sexual behavior. We propose that this similarity …
Amygdala and anterior cingulate transcriptomes from individuals with bipolar disorder reveal downregulated neuroimmune and synaptic pathways
Recent genetic studies have identified variants associated with bipolar disorder (BD), but it
remains unclear how brain gene expression is altered in BD and how genetic risk for BD may …
remains unclear how brain gene expression is altered in BD and how genetic risk for BD may …
[HTML][HTML] Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs
EE Burke, JG Chenoweth, JH Shin… - Nature …, 2020 - nature.com
Human induced pluripotent stem cells (hiPSCs) are a powerful model of neural differentiation
and maturation. We present a hiPSC transcriptomics resource on corticogenesis from 5 …
and maturation. We present a hiPSC transcriptomics resource on corticogenesis from 5 …
Profiling gene expression in the human dentate gyrus granule cell layer reveals insights into schizophrenia and its genetic risk
…, T Saito, L Blanpain, J Ukaigwe, EE Burke… - Nature …, 2020 - nature.com
Specific cell populations may have unique contributions to schizophrenia but may be missed
in studies of homogenate tissue. Here laser capture microdissection followed by RNA …
in studies of homogenate tissue. Here laser capture microdissection followed by RNA …
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder
Autism spectrum disorder (ASD) is genetically heterogeneous with convergent
symptomatology, suggesting common dysregulated pathways. In this study, we analyzed brain …
symptomatology, suggesting common dysregulated pathways. In this study, we analyzed brain …
[HTML][HTML] Endocytosis resumes during late mitosis and is required for cytokinesis
JK Schweitzer, EE Burke, HV Goodson… - Journal of Biological …, 2005 - ASBMB
Recent work has underscored the importance of membrane trafficking events during cytokinesis.
For example, targeted membrane secretion occurs at the cleavage furrow in animal cells…
For example, targeted membrane secretion occurs at the cleavage furrow in animal cells…
[HTML][HTML] Comprehensive assessment of multiple biases in small RNA sequencing reveals significant differences in the performance of widely used methods
C Wright, A Rajpurohit, EE Burke, C Williams… - BMC genomics, 2019 - Springer
Background RNA sequencing offers advantages over other quantification methods for
microRNA (miRNA), yet numerous biases make reliable quantification challenging. Previous …
microRNA (miRNA), yet numerous biases make reliable quantification challenging. Previous …