During limb regeneration adult tissue is converted into a zone of undifferentiated progenitors
called the blastema that reforms the diverse tissues of the limb. Previous experiments have …

Recent advances in limb regeneration are revealing the molecular events that integrate
growth control, cell fate programming, and positional information to yield the exquisite …

Salamanders serve as important tetrapod models for developmental, regeneration and
evolutionary studies. An extensive molecular toolkit makes the Mexican axolotl (Ambystoma …

The ability of animals to regenerate missing parts is a dramatic and poorly understood aspect
of biology. The sources of new cells for these regenerative phenomena have been sought …

For many years the mammalian CNS has been seen as an organ that is unable to regenerate.
However, it was also long known that lower vertebrate species are capable of impressive …

To understand how microtubules are generated in the growth cone, we have imaged
fluorescently tagged microtubules in living frog embryonic neurons. The neurons were labeled by …

… Schellbach for sequencing; and members of the Tanaka lab and the Treutlein lab and S.
Pääbo for helpful discussions. We thank the Core Unit Durchflusszytometrie (CUDZ) at the …

Salamanders regenerate appendages via a progenitor pool called the blastema. The
cellular mechanisms underlying regeneration of muscle have been much debated but have …

Foreign environments may induce adult stem cells to switch lineages and populate multiple
tissue types, but whether this mechanism is used for tissue repair remains uncertain. …

The simultaneous overexpression of several transcription factors has emerged as a successful
strategy to convert fibroblasts into other cell types including pluripotent cells, neurons, …