User profiles for E. Fiorillo

Edoardo Fiorillo

- Verified email at irgb.cnr.it - Cited by 4943

Edoardo Fiorillo

- Verified email at ibe.cnr.it - Cited by 835

Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use

…, GE Davies, CB Eaton, MA Ehringer, T Esko, E Fiorillo… - Nature …, 2019 - nature.com
Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

The power of genetic diversity in genome-wide association studies of lipids

…, M Sabater-Lleal, R Noordam, C Sidore, E Fiorillo… - Nature, 2021 - nature.com
Increased blood lipid levels are heritable risk factors of cardiovascular disease with varied
prevalence worldwide owing to different dietary patterns and medication use 1 . Despite …

[HTML][HTML] Genetic diversity fuels gene discovery for tobacco and alcohol use

…, T Esko, JD Faul, L Fernandes Silva, E Fiorillo… - Nature, 2022 - nature.com
Tobacco and alcohol use are heritable behaviours associated with 15% and 5.3% of worldwide
deaths, respectively, due largely to broad increased risk for disease and injury 1 , 2 , 3 – …

[HTML][HTML] The longitudinal dynamics and natural history of clonal haematopoiesis

MA Fabre, JG de Almeida, E Fiorillo, E Mitchell… - Nature, 2022 - nature.com
e, Representation of extrapolated trajectories derived from longitudinal data, assuming stable
lifelong growth at the same fixed rate we observed during older age; some projections are …

A flexible unmanned aerial vehicle for precision agriculture

…, SF Di Gennaro, E Fiorillo, L Genesio, E Lugato… - Precision …, 2012 - Springer
An unmanned aerial vehicle (“VIPtero”) was assembled and tested with the aim of developing
a flexible and powerful tool for site-specific vineyard management. The system comprised …

[HTML][HTML] Overexpression of the cytokine BAFF and autoimmunity risk

…, M Gorospe, D Schlessinger, E Fiorillo… - … England Journal of …, 2017 - Mass Medical Soc
Background Genomewide association studies of autoimmune diseases have mapped hundreds
of susceptibility regions in the genome. However, only for a few association signals has …

[HTML][HTML] Genetic variants regulating immune cell levels in health and disease

…, CM Jones, D Schlessinger, GR Abecasis, E Fiorillo… - Cell, 2013 - cell.com
E) HLA-DR activation marker was analyzed on NK-gated cells. F) NKT cells were isolated
considering their positivity for CD3, CD16 and/or CD56 antigens. G) Activated T cells were …

[HTML][HTML] Genome-wide analyses identify a role for SLC17A4 and AADAT in thyroid hormone regulation

…, JG Eriksson, L Ferrrucci, T Fiers, E Fiorillo… - Nature …, 2018 - nature.com
Thyroid dysfunction is an important public health problem, which affects 10% of the general
population and increases the risk of cardiovascular morbidity and mortality. Many aspects of …

[HTML][HTML] Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection

…, JA Meunier, M Steri, N Harper, E Fiorillo… - Nature …, 2023 - nature.com
Some people remain healthier throughout life than others but the underlying reasons are
poorly understood. Here we hypothesize this advantage is attributable in part to optimal …

Complex genetic signatures in immune cells underlie autoimmunity and inform therapy

…, M Floris, M Pala, D Schlessinger, E Fiorillo… - Nature …, 2020 - nature.com
… . c–e, Association profiles for the autoimmune diseases MS (c), RA (d) and IBD (e). The data
… Genes, position of exons and direction of transcription are noted below e. The plots were …