Phase separation of a yeast prion protein promotes cellular fitness

…, A Pozniakovsky, J Mahamid, AS Holehouse, E Nüske… - Science, 2018 - science.org
… (E) Translational activity was determined for cells expressing WT Sup35 and Sup35C during
exponential growth (first data point), during 60 min of energy depletion (ED; highlighted in …

Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules

…, S Maharana, D Mateju, L Malinovska, E Nüske… - elife, 2015 - elifesciences.org
… (E) Fluorescence recovery after photobleaching analysis of Lsm4 in the P body state (induced
by glucose depletion) or amyloid-like state. Dendra2-tagged Lsm4 was expressed from a …

Filament formation by metabolic enzymes is a specific adaptation to an advanced state of cellular starvation

I Petrovska, E Nüske, MC Munder, G Kulasegaran… - elife, 2014 - elifesciences.org
… Petrovska, Nüske et al. now reveal more about how and why an enzyme called glutamine
synthetase (Gln1) forms filaments in yeast cells. Gln1 has a cylindrical shape. This shape …

A pH-driven transition of the cytoplasm from a fluid-to a solid-like state promotes entry into dormancy

…, T Franzmann, E Nuske, O Otto, M Herbig, E Ulbricht… - elife, 2016 - elifesciences.org
10.7554/eLife.09347.001 Cells can enter into a dormant state when faced with unfavorable
conditions. However, how cells enter into and recover from this state is still poorly understood…

Reorganization of budding yeast cytoplasm upon energy depletion

G Marini, E Nüske, W Leng, S Alberti… - Molecular biology of the …, 2020 - Am Soc Cell Biol
… (C, F, G, H) Slices through tomographic reconstructions of the same cells as in B and E. (G,
H) Magnified views of the tomographic slices shown in C and F, respectively. Bundles of …

Perceived stigma and self-stigma of problem gambling: Perspectives of people with gambling problems

N Hing, E Nuske, SM Gainsbury… - International Gambling …, 2016 - Taylor & Francis
Minimal research has investigated the stigma associated with problem gambling, despite its
major hindrance to help-seeking and recovery. This study explored perceived stigma and …

[HTML][HTML] The public stigma of problem gambling: Its nature and relative intensity compared to other health conditions

…, AMT Russell, SM Gainsbury, E Nuske - Journal of Gambling …, 2016 - Springer
Problem gambling attracts considerable public stigma, with deleterious effects on mental
health and use of healthcare services amongst those affected. However, no research has …

Filament formation by the translation factor eIF2B regulates protein synthesis in starved cells

E Nüske, G Marini, D Richter, W Leng… - Biology …, 2020 - journals.biologists.com
… (E) Ultrastructure of eIF2B filaments as found in energy depleted cells by correlative light
and electron microscopy (CLEM). Left: electron micrograph of one representative cell overlaid …

[PDF][PDF] Gamblers at-risk and their help-seeking behaviour

N Hing, E Nuske, S Gainsbury - Melbourne: Gambling Research …, 2012 - researchgate.net
It is estimated that only 10 per cent of problem gamblers in Australia seek formal assistance
for their problems(Delfabbro, 2008). This is despite a range of free treatment services …

[HTML][HTML] Impacts of gambling problems on partners: Partners' interpretations

L Holdsworth, E Nuske, M Tiyce, N Hing - Asian Journal of Gambling …, 2013 - Springer
Partners can be especially vulnerable to the negative effects of gambling problems, but little
research has sought to understand partners’ experiences from their own unique …