Pulmonary complications of congenital heart disease

F Healy, BD Hanna, R Zinman - Paediatric respiratory reviews, 2012 - Elsevier
Cardiac and pulmonary pathophysiologies are closely interdependent, which makes the
management of patients with congenital heart disease (CHD) all the more complex. Pulmonary …

Gathering time: dating the early Neolithic enclosures of southern Britain and Ireland

A Whittle, A Bayliss, F Healy - 2011 - torrossa.com
Gathering Time presents the results of a major dating programme that re-writes the early
Neolithic of Britain by more accurately dating enclosures, a phenomenon that first appeared in …

The txtAB genes of the plant pathogen Streptomyces acidiscabies encode a peptide synthetase required for phytotoxin thaxtomin A production and pathogenicity

FG Healy, M Wach, SB Krasnoff… - Molecular …, 2000 - Wiley Online Library
… acidiscabies cosmid libraries; Southern hybridization data suggest that this synthetase is
not present in the other plant pathogenic species (FG Healy and R. Loria, unpublished). …

Direct isolation of functional genes encoding cellulases from the microbial consortia in a thermophilic, anaerobic digester maintained on lignocellulose

FG Healy, RM Ray, HC Aldrich, AC Wilkie… - Applied microbiology …, 1995 - Springer
Gene libraries (“zoolibraries”) were constructed in Escherichia coli using DNA isolated from
the mixed liquor of thermophilic, anaerobic digesters, which were in continuous operation …

The importance of Ras in drug resistance in cancer

FM Healy, IA Prior, DJ MacEwan - British Journal of …, 2022 - Wiley Online Library
In this review, we analyse the impact of oncogenic Ras mutations in mediating cancer drug
resistance and the progress made in the abrogation of this resistance, through …

[HTML][HTML] Worked to the bone: antibody-based conditioning as the future of transplant biology

JM Griffin, FM Healy, LN Dahal, Y Floisand… - Journal of Hematology & …, 2022 - Springer
Conditioning of the bone marrow prior to haematopoietic stem cell transplant is essential in
eradicating the primary cause of disease, facilitating donor cell engraftment and avoiding …

[HTML][HTML] Imatinib therapy for patients with recent-onset type 1 diabetes: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

…, C Evans-Molina, C Ferrara, F Healy… - The Lancet Diabetes & …, 2021 - thelancet.com
Background Type 1 diabetes results from autoimmune-mediated destruction of β cells. The
tyrosine kinase inhibitor imatinib might affect relevant immunological and metabolic pathways…

Pyruvate Formate Lyase and Acetate Kinase Are Essential for Anaerobic Growth of Escherichia coli on Xylose

A Hasona, Y Kim, FG Healy, LO Ingram… - Journal of …, 2004 - Am Soc Microbiol
During anaerobic growth of bacteria, organic intermediates of metabolism, such as pyruvate
or its derivatives, serve as electron acceptors to maintain the overall redox balance. Under …

Involvement of a Cytochrome P450 Monooxygenase in Thaxtomin A Biosynthesis by Streptomyces acidiscabies

FG Healy, SB Krasnoff, M Wach, DM Gibson… - Journal of …, 2002 - Am Soc Microbiol
The biosynthesis of the thaxtomin cyclic dipeptide phytotoxins proceeds nonribosomally via
the thiotemplate mechanism. Acyladenylation, thioesterification, N-methylation, and …

The role of short-chain fatty acids, produced by anaerobic bacteria, in the cystic fibrosis airway

…, AA Azim, C Gunaratnam, F Healy… - American journal of …, 2015 - atsjournals.org
… parvula and F. nucleatum displayed more complex SCFA secretomes consisting of acetic
and … parvula and F. nucleatum was equal to or greater than that induced by the major CF …